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中国献血者人群丙氨酸氨基转移酶血液筛查策略调整专家共识

国家卫生健康委临床检验中心血液筛查专家组 曾劲峰 王露楠 张传宝 马洁 王瑞 王淏 臧亮 黄力勤 常乐 何敏 郑欣 党英男

中国输血杂志2025,Vol.38Issue(4):455-464,10.
中国输血杂志2025,Vol.38Issue(4):455-464,10.DOI:10.13303/j.cjbt.issn.1004-549x.2025.04.001

中国献血者人群丙氨酸氨基转移酶血液筛查策略调整专家共识

Expert consensus on the adjustment of blood screening strategy for alanine aminotransferase in Chinese blood do-nors

国家卫生健康委临床检验中心血液筛查专家组 1曾劲峰 1王露楠 1张传宝 1马洁 1王瑞 1王淏 1臧亮 1黄力勤 1常乐 1何敏 1郑欣 1党英男1

作者信息

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摘要

Abstract

Alanine aminotransferase(ALT),as a non-specific alternative test for hepatitis detection,was listed as a mandatory screening item for blood donors in China in the 1990s and has been continued to this day.However,as a non-specific indicator of viral infection,the elevation of ALT is easily affected by various factors,resulting in some healthy blood donors being unable to donate blood due to a temporary increase in ALT levels,which leads to a waste of blood resources.Based on previous research findings and preliminary survey data,this expert consensus focuses on optimizing the ALT screening strategy,aiming to provide comprehensive and professional guidance for verifying the effectiveness of ALT testing in blood donors,adjusting the testing strategy,and the practical operation in ALT screening.

关键词

丙氨酸氨基转移酶/筛查策略/合格标准/质量保证

Key words

alanine aminotransferase/screening strategy/eligibility criteria/quality assurance

分类

临床医学

引用本文复制引用

国家卫生健康委临床检验中心血液筛查专家组,曾劲峰,王露楠,张传宝,马洁,王瑞,王淏,臧亮,黄力勤,常乐,何敏,郑欣,党英男..中国献血者人群丙氨酸氨基转移酶血液筛查策略调整专家共识[J].中国输血杂志,2025,38(4):455-464,10.

基金项目

四大慢病重大专项(2024ZD0523703) (2024ZD0523703)

深圳市医疗卫生三名工程(SZSM202311032) (SZSM202311032)

中国输血杂志

1004-549X

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