中国输血杂志2025，Vol.38Issue(4)：557-561,5.DOI:10.13303/j.cjbt.issn.1004-549x.2025.04.015
2例贝林妥欧单抗输注新模式的报告
Novel outpatient infusion model of blinatumomab:case studies of two patients
力桂君 1蒋雪梅 1王馨 1徐秋霞 1李建辉 1代素思 1何莹 1易海 1陈丹1
作者信息
- 1. 中国人民解放军西部战区总医院 血液科,四川 成都 610000
- 折叠
摘要
Abstract
Objective To evaluate the feasibility of a novel outpatient infusion model for blinatumomab in two acute lymphoblastic leukemia(ALL)patients,aiming to address challenges of poor treatment tolerance,high healthcare costs,and compromised quality of life,thereby providing clinical insights for broader adoption of this approach.Methods Two post-allogeneic hematopoietic stem cell transplantation(allo-HSCT)patients undergoing blinatumomab maintenance therapy were selected to evaluate the efficacy of the outpatient infusion model.Patient selection criteria,nursing protocols,standard-ized workflows,and advancements in infusion practices were systematically analyzed combined with a review of global devel-opments in this field.Results Both patients completed outpatient blinatumomab infusion without severe adverse events,demonstrating preliminary feasibility and safety of this model.The novel approach enhanced treatment convenience,reduced hospitalization costs,and improved quality of life.Conclusion Despite the limited sample size,this pilot study highlights the potential of outpatient blinatumomab administration as a viable alternative to traditional inpatient regimens.关键词
贝林妥欧单抗/急性淋巴细胞白血病/院外输注Key words
blinatumomab/acute lymphoblastic leukemia(ALL)/outpatient infusion分类
医药卫生引用本文复制引用
力桂君,蒋雪梅,王馨,徐秋霞,李建辉,代素思,何莹,易海,陈丹..2例贝林妥欧单抗输注新模式的报告[J].中国输血杂志,2025,38(4):557-561,5.
