中药材2024，Vol.47Issue(12)：3028-3033,6.DOI:10.13863/j.issn1001-4454.2024.12.015
凹叶瓜馥木的化学成分研究
Chemical Constituents of Fissistigma retusum
摘要
Abstract
Objective:To study the chemical constituents of Fissistigma retusum.Methods:Silica gel column chromatography,Seph-adex LH-20 column chromatography and semi-preparative HPLC were used to isolate and purified the 95%ethanol extract of Fissistigma retusum,and the structures were identified by physicochemical properties and spectral data.Results:Twenty compounds were isolated from Fissistigma retusum and identified as goniopedaline(1),aristolactam AⅢa(2),piperolactam A(3),piperolactam B(4),aristolo-lacttam AⅠa(5),aristolactam BⅡ(6),aristololactam AⅡ(7),O-methylmoscatoline(8),lysicamine(9),ethyl 4-hydroxybenzoate(10),ethyl 3,4-dihydroxybenzoate(11),telisatins A(12),telisatins B(13),5,6,7,8-tetramethoxyflavone(14),7-hydroxyl-5,6,8-tet-ramethoxyflavone(15),2-hydroxyl-3,4,5,6-tetramethoxydihydrochalcone(16),(+)-syringaresinol(17),(+)-isolariciresinol(18),2,6-dimethoxy-p-benzoquinone(19),(+)-bosciali(20),respectively.Conclusion:Among them,compounds 4,12,13,16 to 20 are isolated from Fissistigma genus for the first time.关键词
凹叶瓜馥木/化学成分/分离鉴定/酰胺生物碱/黄酮Key words
Fissistigma retusum(Lév.)Rehd./Chemical constituents/Isolation and identification/Amide alkaloids/Flavonoid分类
中医学引用本文复制引用
何颖,金晨,刘会珍,赵灼斌,黄新文,黄祥威,黄慧莲..凹叶瓜馥木的化学成分研究[J].中药材,2024,47(12):3028-3033,6.基金项目
国家自然科学基金项目(82160792) （82160792）
江西省自然科学基金重点项目(20232ACB206059) （20232ACB206059）
江西中医药大学校级科技创新团队发展计划(CXTD22002) （CXTD22002）
江西中医药大学校级研究生创新专项(JZYC23S63) （JZYC23S63）
