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莲房的化学成分研究

张贵兰 陈日荣 李佳东 吴弢

中药材2024,Vol.47Issue(12):3042-3047,6.
中药材2024,Vol.47Issue(12):3042-3047,6.DOI:10.13863/j.issn1001-4454.2024.12.017

莲房的化学成分研究

Chemical Constituents from the Receptacle of Nelumbo nucifera

张贵兰 1陈日荣 1李佳东 1吴弢1

作者信息

  • 1. 上海中医药大学中药研究所/上海中药标准化研究中心,上海 201203
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摘要

Abstract

Objective:To study the chemical constituents of Nelumbo nucifera receptacle.Methods:The ethanol extract of Nelumbo nucifera was isolated and purified by silica gel column,ODS column,Sephadex LH-20,preparative HPLC and other techniques.The structures were identified by ESI-MS,NMR and other spectral data.Results:Sixteen compounds were isolated from Nelumbo nucifera re-ceptacle and identified as 23-hydroxy-betulinic acid-28-O-β-D-glucopyranoside(1),maesopsin-6-O-β-D-glucopyranoside(2),rhamne-tin-3-O-β-D-glucuronide-6″-methyl ester(3),(22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one(4),quercetin-3-O-α-L-arabinopyrano-side(5),nelumnucifoside B(6),kaempferol-7-O-β-D-glucoside(7),isorhamnetin-3-O-β-D-glucoside(8),lysicamine(9),quercetin-3-O-β-D-glucuronide(10),hyperoside(11),kaempferol-3-O-β-D-galactoside(12),isorhamnetin-3-O-β-D-galactoside(13),syringetin-3-O-β-D-glucoside(14),isoquercitrin(15),liriodenine(16),respectively.Conclusion:Among them,compounds 1 to 4 are isolated from Nelumbo genus for the first time,and compounds 5 to 9,12,16 are isolated from Nelumbo nucifera for the first time.

关键词

莲房/化学成分/黄酮类/萜类/生物碱类/甾醇类

Key words

Receptacle of Nelumbo nucifera Gaertn./Chemical constituents/Flavonoids/Terpenoids/Alkaloids/Sterols

分类

中医学

引用本文复制引用

张贵兰,陈日荣,李佳东,吴弢..莲房的化学成分研究[J].中药材,2024,47(12):3042-3047,6.

基金项目

上海市2022年度"科技创新行动计划"技术标准项目(22DZ2204100) (22DZ2204100)

中药材

OA北大核心CSTPCD

1001-4454

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