中药材2024,Vol.47Issue(12):3042-3047,6.DOI:10.13863/j.issn1001-4454.2024.12.017
莲房的化学成分研究
Chemical Constituents from the Receptacle of Nelumbo nucifera
摘要
Abstract
Objective:To study the chemical constituents of Nelumbo nucifera receptacle.Methods:The ethanol extract of Nelumbo nucifera was isolated and purified by silica gel column,ODS column,Sephadex LH-20,preparative HPLC and other techniques.The structures were identified by ESI-MS,NMR and other spectral data.Results:Sixteen compounds were isolated from Nelumbo nucifera re-ceptacle and identified as 23-hydroxy-betulinic acid-28-O-β-D-glucopyranoside(1),maesopsin-6-O-β-D-glucopyranoside(2),rhamne-tin-3-O-β-D-glucuronide-6″-methyl ester(3),(22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one(4),quercetin-3-O-α-L-arabinopyrano-side(5),nelumnucifoside B(6),kaempferol-7-O-β-D-glucoside(7),isorhamnetin-3-O-β-D-glucoside(8),lysicamine(9),quercetin-3-O-β-D-glucuronide(10),hyperoside(11),kaempferol-3-O-β-D-galactoside(12),isorhamnetin-3-O-β-D-galactoside(13),syringetin-3-O-β-D-glucoside(14),isoquercitrin(15),liriodenine(16),respectively.Conclusion:Among them,compounds 1 to 4 are isolated from Nelumbo genus for the first time,and compounds 5 to 9,12,16 are isolated from Nelumbo nucifera for the first time.关键词
莲房/化学成分/黄酮类/萜类/生物碱类/甾醇类Key words
Receptacle of Nelumbo nucifera Gaertn./Chemical constituents/Flavonoids/Terpenoids/Alkaloids/Sterols分类
中医学引用本文复制引用
张贵兰,陈日荣,李佳东,吴弢..莲房的化学成分研究[J].中药材,2024,47(12):3042-3047,6.基金项目
上海市2022年度"科技创新行动计划"技术标准项目(22DZ2204100) (22DZ2204100)