湖南工业大学学报2025，Vol.39Issue(5)：67-73,7.DOI:10.3969/j.issn.1673-9833.2025.05.010
聚乙二醇基双网络水凝胶作为类软骨材料的研究
Study on the Application of PEG-Based Double Network Hydrogel to Cartilage Replacement
摘要
Abstract
By using polyacrylate-co-acrylamide and linear polyethylene glycol(PEG)as the first and second networks respectively,the double network hydrogels with mechanical properties of cartilage have thus been prepared by photopolymerization.The successful synthesis of hydrogel is verified by Fourier infrared spectroscopy,with its swelling property calculated by weighing method,followed by a test of its mechanical properties by a universal tensile testing machine.The results show that the stress of the prepared hydrogel is about 1.82 MPa under 304%tensile strain;while under 80%compression strain,the stress is approximately 10.36 MPa,with the hydrogel effectively dissipating energy with high toughness(3.37 MJ/m3).After 10 cycles,the peak stress remains at 99.1%of the initial stress value with a low swelling rate of 2.16.It can be seen that this double network cross-linking condition improves significantly the self-recovery and anti-fatigue properties of the hydrogel,characterized with fine anti-swelling properties,which makes it a new potential cartilage-like material.关键词
类软骨材料/双网络水凝胶/聚乙二醇/力学性能/溶胀性能Key words
cartilage-like material/double network hydrogel/polyethylene glycol/mechanical property/swelling property分类
化学工程引用本文复制引用
刘晓旭,周贵寅..聚乙二醇基双网络水凝胶作为类软骨材料的研究[J].湖南工业大学学报,2025,39(5):67-73,7.基金项目
国家自然科学基金资助项目(52070078) （52070078）
湖南省教育厅科学研究基金资助项目(23A0451) （23A0451）
湖南省自然科基金项目:学基金资助项目(2024JJ7138) （2024JJ7138）
