中药材2024，Vol.47Issue(5)：1130-1135,6.DOI:10.13863/j.issn1001-4454.2024.05.010
基于多指标评价不同生长年限桔梗的药材质量
Study on the Quality of Platycodonis Radix with Different Growth Years Based on Multi-Indicator Evaluation
摘要
Abstract
Objective:To evaluate the quality of Platycodonis Radix in different growing years by using common methods and clas-sical indexes.Methods:With different growth years of Platycodonis Radix as the research object,the morphological characteristics,drying rate,total ash and extract content of Platycodonis Radix were measured,respectively.The contents of deapi-platycoside E,platycodin E,platycodin D3,deapio-platycodin D,platycodin D2,platycodin D in Platycodonis Radix with different growing years were determined by HPLC.The quality of Platycodonis Radix with different growing years was analyzed by principal component analysis and orthogonal par-tial least square discriminant analysis.Results:The quality of Platycodonis Radix was different in different growing years.The appear-ance traits,alcohol-soluble extracts and platycodins content of three-year-old Platycodonis Radix were all in line with the provisions of the 2020 edition of Chinese Pharmacopoeia.With the increase of growth years,the total concent of six saponins in one-year Platycodonis Radix was the least,and the total content of six saponins in three-year Platycodonis Radix was the highest.Conclusion:Based on the a-nalysis rasults of various indexes,the quality of three-year-old Platycodonis Radix is the best.This study aunmulates a solid foundation for further exploring the mechanism of forming the quality of Platycodonis Radix.关键词
桔梗/生长年限/含量测定/多元统计分析/质量评价Key words
Platycodonis Radix/Growth years/Content determination/Multivariate statistical analysis/Quality evaluation分类
医药卫生引用本文复制引用
井亚江,黄建萍,王七龙,张岗,彭亮,王昌利,颜永刚..基于多指标评价不同生长年限桔梗的药材质量[J].中药材,2024,47(5):1130-1135,6.基金项目
内蒙古自治区科技重大专项(2019ZD005) （2019ZD005）
陕西中医药大学"秦药"品质评价与资源开发学科创新团队项目(2019-QN01) （2019-QN01）
国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人函[2019]41号) （国中医药人函[2019]41号）
第二批省级中医药中青年科技骨干人才(2023-ZQNY-003) （2023-ZQNY-003）
