浙江大学学报（医学版）2025，Vol.54Issue(2)：167-174,8.DOI:10.3724/zdxbyxb-2024-0414
经导管主动脉瓣置换术相关脑卒中研究进展
Advances in stroke after transcatheter aortic valve replacement
摘要
Abstract
With the clinical generalization and popularization of transcatheter aortic valve replacement(TAVR),cerebrovascular events related to TAVR occur more frequently,which significantly impairs neurocognitive function,increases mortality,and seriously affects prognosis and quality of life in these patients.However,the reported incidence rates of TAVR-related stroke differ in literature due to inconsistent diagnostic criteria.According to the onset time,TAVR-related stroke can be divided into acute(≤24 h),subacute(24 h30 d),early(31 d1 year)and late(＞1 year)types,and the cause of stroke generally varies according to the onset time.Both surgical(balloon aortic valvuloplasty,types of transcatheter heart valve,alternative access)and non-surgical(valvular calcium burden,bicuspid aortic valve,subclinical leaflet thrombosis,postoperative new-onset atrial fibrillation)can be related to the occurrence of TAVR-related stroke.Postprocedural monitoring,postprocedural antithrombotic therapy,and cerebral embolic protection devices are important for the prevention of TAVR-related stoke.This article reviews the research progress on TAVR-related stroke,focusing on its epidemiology,risk factors and preventive measures,aiming to provide reference for the clinical management of stroke in TAVR.关键词
经导管主动脉瓣置换术/脑血管事件/脑卒中/综述Key words
Transcatheter aortic valve replacement/Cerebrovascular events/Stroke/Review分类
医药卫生引用本文复制引用
周越,杨人强..经导管主动脉瓣置换术相关脑卒中研究进展[J].浙江大学学报（医学版）,2025,54(2):167-174,8.基金项目
国家自然科学基金(82360083) （82360083）
江西省自然科学基金(20212BAB216045)This work was supported by the National Natural Science Foundation of China(82360083),Natural Science Foundation of Jiangxi Province(20212BAB216045) （20212BAB216045）
