针灸和草药（英文）2025，Vol.5Issue(1)：1-22,22.DOI:10.1097/HM9.0000000000000147
中药水煎剂中多糖的作用机制
Action mechanisms of polysaccharides in Chinese herbal decoctions
徐文锋 1赵静 2李绍平2
作者信息
- 1. 澳门大学-国家糖工程技术研究中心中药糖工程与检测技术联合实验室,澳门||澳门大学中药质量研究国家重点实验室,澳门
- 2. 澳门大学-国家糖工程技术研究中心中药糖工程与检测技术联合实验室,澳门||澳门大学中药质量研究国家重点实验室,澳门||澳门大学澳门中药检测中心,澳门||澳门大学健康科学学院药学系,澳门
- 折叠
摘要
Abstract
Water decoction is the main form of traditional Chinese medicine(TCM)administered in clinics.Polysaccharides are major components of decoction.Recent studies reported that polysaccharides possess multiple pharmacological activities.However,the mechanism by which oral Chinese herbal polysaccharides play vital roles in the body remains uncertain.This review discussed the polysaccharides in Chinese herbal decoctions and their effects,direct and indirect.The direct impact of polysaccharides includes being absorbed into the body immunity regulation through Peyer's patches;electrostatic adsorption,hydrophobic interaction,and glycoprotein receptors-induced antibacterial effects;prebiotic functions;gut microbiota structural regulation;and increasing the relative abundance of beneficial bacteria.The indirect effects of the polysaccharides in Chinese herbal decoctions include phytochemical toxicity reduction and activity enhancement.Finally,their clinical and research significance is summarized and future research directions are discussed.关键词
中药/多糖/作用机制/水煎剂/肠道菌群Key words
Action mechanisms/Decoctions/Gut microbiota/Polysaccharides/Traditional Chinese medicines引用本文复制引用
徐文锋,赵静,李绍平..中药水煎剂中多糖的作用机制[J].针灸和草药（英文）,2025,5(1):1-22,22.
