针灸和草药（英文）2025，Vol.5Issue(1)：36-45,10.DOI:10.1097/HM9.0000000000000142
内源性大麻素系统参与疼痛调节和电针镇痛的研究进展
Research progress regarding endocannabinoid system involvement in pain modulation and electroacupuncture analgesia
秦仁杰 1吴益松 1金诺 1徐行知 1蓝渝叶 1景向红 2李熳1
作者信息
- 1. 华中科技大学同济医学院基础医学院,教育部麻醉与复苏重点实验室,武汉
- 2. 中国中医研究院院针灸研究所,北京
- 折叠
摘要
Abstract
Pain is a subjective and unpleasant sensation that significantly impacts the daily lives of individuals.Chronic pain represents one of the most challenging public health issues,and ensuring effective pain management is a fundamental right of individuals and a sacred duty of healthcare providers.Cannabis,one of the earliest recognized medicinal plants,contains cannabinoids,which are non-opioid substances that modulate nociceptive responses.Electroacupuncture(EA),characterized by its low-risk and well-tolerated nature,is pivotal in pain management.The endocannabinoid system consists of endocannabinoids,cannabinoid receptors,and enzymes involved in endocannabinoid synthesis,degradation,and transport.Recently,the role of the endocannabinoid system in pain development and EA analgesia has attracted considerable research attention.Studies have highlighted the role of the endocannabinoid system in various types of pain,including inflammatory pain,neuropathic pain,and cancer-related pain,as well as in EA analgesia.This study aims to review the mechanisms of endocannabinoid system involvement in pain modulation and EA analgesia to provide insights to inform clinical approaches to pain management.关键词
内源性大麻素受体/电针/炎症性疼痛/神经性疼痛Key words
Electroacupuncture/Endocannabinoid receptors/Inflammatory pain/Neuropathic pain引用本文复制引用
秦仁杰,吴益松,金诺,徐行知,蓝渝叶,景向红,李熳..内源性大麻素系统参与疼痛调节和电针镇痛的研究进展[J].针灸和草药（英文）,2025,5(1):36-45,10.
