针灸和草药（英文）2025，Vol.5Issue(1)：46-56,11.DOI:10.1097/HM9.0000000000000151
黑籽(黑种草)免疫调节作用的临床与临床前证据综述
Review of the current clinical and preclinical evidence pertaining to the immunomodulatory effects of black seeds(Nigella sativa)
Rajkapoor Balasubramanian 1Naina Mohamed Pakkir Maideen 2Arun Shanmugam3
作者信息
- 1. Department of Pharmacology,J.K.K.Nattraja College of Pharmacy,Komarapalayam-638 183,India 印度
- 2. Pharmacologist,Dubai Academic Health Corporation,Dubai,UAE迪拜
- 3. Department of Pharmacy Practice,J.K.K.Nattraja College of Pharmacy,Komarapalayam-638 183,India印度
- 折叠
摘要
Abstract
Humans and other vertebrates are safeguarded from invading pathogenic microbes by the immune system.Black seed,scientifically known as Nigella sativa,has garnered attention for its potential immunomodulatory effects in both clinical and preclinical studies.This comprehensive review aims to consolidate and analyze the existing body of evidence surrounding the immunological impact of black seeds.In this review,we analyze the immunomodulatory potentials of black seeds(N.sativa).For the purpose of finding pertinent publications,the literatures was searched in web-based databases,including Web of Science,Medline/PMC/PubMed,Embase,EBSCO,Google Scholar,Science Direct,and reference lists.Several clinical,in vivo,and in vitro studies have demonstrated that supplementation with black seeds(N.sativa)has potential immunomodulatory activity.Black seeds(N.sativa)may influence immune responses through a variety of mechanisms.By synthesizing and critically assessing the current state of knowledge on the immunomodulatory effects of black seeds,this review aims to provide valuable insights into the potential therapeutic uses and future research directions for harnessing the immunological benefits of this natural remedy.关键词
黑籽/免疫调节/干扰素/淋巴细胞Key words
Black seeds/Immunomodulation/Immunostimulation/Immunosuppression/Interferon/Lymphocytes/Nigella sativa引用本文复制引用
Rajkapoor Balasubramanian,Naina Mohamed Pakkir Maideen,Arun Shanmugam..黑籽(黑种草)免疫调节作用的临床与临床前证据综述[J].针灸和草药（英文）,2025,5(1):46-56,11.
