针灸和草药（英文）2025，Vol.5Issue(1)：57-67,11.DOI:10.1097/HM9.0000000000000143
中医药大语言模型:系统综述
Large language models in traditional Chinese medicine:a systematic review
陈哲 1王辉 2李承贤 3刘春香 2杨丰文 2张冬 2Alice Josephine Fauci 4张俊华3
作者信息
- 1. 天津中医药大学循证医学中心,天津||现代中医药海河实验室,天津||现代中药创制全国重点实验室,天津
- 2. 天津中医药大学循证医学中心,天津
- 3. 天津中医药大学循证医学中心,天津||现代中医药海河实验室,天津
- 4. 意大利国家卫生研究院,意大利
- 折叠
摘要
Abstract
Objective:Generative artificial intelligence(AI)technology,represented by large language models(LLMs),has gradually been developed for traditional Chinese medicine(TCM);however,challenges remain in effectively enhancing AI applications for TCM.Therefore,this study is the first systematic review to analyze LLMs in TCM retrospectively,focusing on and summarizing the evidence of their performance in generative tasks.
Methods:We extensively searched electronic databases for articles published until June 2024 to identify publicly available studies on LLMs in TCM.Two investigators independently selected and extracted the related information and evaluation metrics.Based on the available data,this study used descriptive analysis for a comprehensive systematic review of LLM technology related to TCM.
Results:Ten studies published between 2023 and 2024 met our eligibility criteria and were included in this review,including 40%LLMs in the TCM vertical domain,40%containing TCM data,and 20%honoring the TCM contribution,with a foundational model parameter range from 1.8 to 33 billion.All included studies used manual or automatic evaluation metrics to evaluate model performance and fully discussed the challenges and contributions through an overview of LLMs in TCM.
Conclusions:LLMs have achieved significant advantages in TCM applications and can effectively address intelligent TCM tasks.Further in-depth development of LLMs is needed in various vertical TCM fields,including clinical and fundamental research.Focusing on the functional segmentation development direction of generative AI technologies in TCM application scenarios to meet the practical needs-oriented demands of TCM digitalization is essential.关键词
大语言模型/中医药/生成式人工智能/系统综述/智能临床应用Key words
Generative artificial intelligence/Intelligence clinical applications/Large language model/Systematic review/Traditional Chinese medicine引用本文复制引用
陈哲,王辉,李承贤,刘春香,杨丰文,张冬,Alice Josephine Fauci,张俊华..中医药大语言模型:系统综述[J].针灸和草药（英文）,2025,5(1):57-67,11.
