中国中西医结合杂志2025，Vol.45Issue(4)：404-409,6.DOI:10.7661/j.cjim.20241106.299
4 057例痛风患者中医证候及证候要素分布特征分析
Laws of Distributions of Chinese Medicine Syndrome Types and Elements in 4 057 Gout Patients:A Retrospective Analysis
摘要
Abstract
Objective To analyze the distribution patterns and characteristics of Chinese medicine(CM)syndromes and elements in patients with gout.Methods A retrospective analysis was conducted in 4 057 gout patients diagnosed and treated by Department of Rheumatism,Guangdong Provincial Hospital of Chinese Medicine.Statistical analyses were performed in CM syndrome types and elements to study their distributional and combinatory patterns of gout.Results(1)Distribution of CM syndromes:The top six most frequently CM syndromes in gout patients were:Pi deficiency with dampness obstruction syndrome(36.09％),damp-heat stagnation syndrome(18.44％),damp-heat accumulation syndrome(13.93％),Pi-Shen deficiency syndrome(7.41％),Gan-Shen deficiency syndrome(4.68％),and Pi deficiency with damp stasis syndrome(4.66％).Of them,male patients had significantly higher proportions of Pi deficiency with dampness obstruction syndrome(1 401/3 764 cases)and damp-heat accumulation syndrome(547/3 764 cases),as compared with female patients(63/293 cases,18/293 cases),with statistical significance(x2=29.124,15.960,P＜0.01).Conversely,female patients exhibited higher proportions of Gan-Shen deficiency syndrome(59/293 cases),Wind-Cold-Damp Bi syndrome(23/293 cases),Pi-Shen deficiency syndrome(40/293 cases),and Qi stagnation with blood stasis syndrome(13/293 cases),as compared with those syndrome in males(131/3 764 cases,37/3 764 cases,261/3 764 cases,26/3 764 cases),with statistical significance(x2=168.945,87.973,17.860,40.069,P＜0.01).The age distribution for gout onset was primarily between 31 and 60 years(64.86％),followed by those over 60(24.34％),and fewer patients under 30(10.81％).(2)Characteristics of CM elements:A total of 19 elements were identified,including 12 pathological elements and 7 pathological location elements.Among the pathological elements,"Dampness"was the most frequently noted(88.37％),highlighting it as the core pathological factor in gout.Other prevalent elements included"Heat"(40.18％)and"Blood Stasis"(30.64％).The most common pathological location element was Pi(54.65％),followed by Shen(14.12％)and Gan(5.47％)Conclusions By integrating the characteristics of CM syndrome typing and elements distributions,Pi deficiency with dampness obstruction syndrome,damp-heat stagnation syndrome,and damp-heat accumulation syndrome were common CM syndromes.The core pathological elements were Pi,dampness,heat,and blood stasis.关键词
痛风/中医证型/中医证素/分布规律/回顾性研究/中西医结合Key words
gout/Chinese medical syndrome type/Chinese medical syndrome element/laws of distributions/retrospective study/integrated Chinese and Western medicine引用本文复制引用
何京谦,伍嘉琪,梁华胜,李李,何晓红,黄清春..4 057例痛风患者中医证候及证候要素分布特征分析[J].中国中西医结合杂志,2025,45(4):404-409,6.基金项目
中医湿证国家重点实验室资助项目(No.SZ2021ZZ3204) （No.SZ2021ZZ3204）
