中国中西医结合杂志2025，Vol.45Issue(4)：416-421,6.DOI:10.7661/j.cjim.20241122.250
四味消疲饮缓解运动性疲劳随机对照研究
Effect of Siwei Xiaopi Yin on Exercise-Induced Fatigue:A Randomized Controlled Study
摘要
Abstract
Objective To evaluate the effectiveness and safety of Siwei Xiaopi Yin(SXY)in treating exercise-induced fatigue.Methods A total of 256 patients with exercise-induced fatigue from a training base were randomly assigned to a treatment group and a control group,128 patients in each group.The treatment group received SXY for 5 days,while the control group received no special intervention.Additionally,40 healthy individuals were recruited as the normal control group.The primary efficacy index was the Rating of Perceived Exertion(RPE),while the secondary efficacy index was the Modified Fatigue Impact Scale(MFIS).Serum lactate,testosterone(T),cortisol(C),urea nitrogen,and lactate dehydrogenase(LDH)levels were tested,and the T/C ratio was calculated.Results All participants completed the study.Of the 256 patients,129 patients were Qi deficiency,67 patients were Yang deficiency,and 60 patients were Yin deficiency.Compared with Yang deficiency,the total MFIS score and cognitive function score were lower in the Qi deficiency and Yin deficiency patients before treatment(P＜0.01).Compared with normal control group,serum lactate,C,urea nitrogen,and LDH levels were higher in the control group(P＜0.01),while T and the T/C ratio were lower(P＜0.01).Compared with control group,the treatment group showed higher levels of T and T/C(P＜0.05),lower serum lactate levels,RPE scores,MFIS total scores,somatic function scores,and cognitive function scores(P＜0.05,P＜0.01),as well as improved clinical efficacy(P＜0.01).No serious adverse reactions were observed in either group.Conclusion SXY effectively reduced serum lactate levels,increased T level and the T/C ratio,and alleviated exercise-induced fatigue.关键词
运动性疲劳/四味消疲饮/随机对照试验/中药复方/中西医结合Key words
exercise-induced fatigue/Siwei Xiaopi Yin/randomized controlled trial/Chinese herbal compound/integrated traditonal Chinese and Western medicine引用本文复制引用
付雅兰,孟宪泽,张瑞荣,缪霆,封颖璐..四味消疲饮缓解运动性疲劳随机对照研究[J].中国中西医结合杂志,2025,45(4):416-421,6.基金项目
军队中医药服务能力培育与提升专项(No.2021ZY015) （No.2021ZY015）
