阿尔茨海默病及相关病2025，Vol.8Issue(3)：200-206,7.DOI:10.3969/j.issn.2096-5516.2025.03.008
MemTrax:一个用于筛查和监测认知变化的数字化连续记忆认知测试工具
MemTrax:a computerized continuous recognition task using in screening and monitoring for cognitive change
摘要
Abstract
Cognitive impairment is the primary symptom of Alzheimer's disease(AD),manifesting as memory loss and changes in other cognitive functions.Currently,cognitive tools such as the mini-mental state examination(MMSE)and the montreal cognitive assessment(MoCA)are widely used to evaluate overall cognitive function in patients.However,these scales are time-consuming and require experienced clinicians to conduct face-to-face testing.This review aims to introduce MemTrax,a computerized continuous recognition task,and its application in cognitive assessment.In this test,subjects are required to complete a picture recognition task within approximately 90 seconds to assess their cognitive functions,mainly episodic memory,including memory processing,storage,retrieval,and reaction time.Previous studies have confirmed that its efficacy in identifying normal individuals,mild cognitive impairment(MCI),and AD patients is superior to MoCA.Moreover,combining with other biomarkers can further enhance its diagnostic efficacy,and it is also potential for assessment of treatment efficacy.Here we also introduce the application of MemTrax in various types of cognitive disorder diseases.Finally,this article proposes that MemTrax can be used as a digital tool to establish a systematic neuroscience database in the future,combining machine learning and other biomarkers to predict early dementia,as well as for large-scale cognitive screening and continuous cognitive monitoring.关键词
认知障碍/MemTrax/情景记忆/数字化认知筛查Key words
Cognitive impairment/MemTrax/Episodic memory/Digital cognitive screening tools分类
临床医学引用本文复制引用
张雅,裴中..MemTrax:一个用于筛查和监测认知变化的数字化连续记忆认知测试工具[J].阿尔茨海默病及相关病,2025,8(3):200-206,7.基金项目
国家自然科学基金项目(82401672) （82401672）
上海医学创新发展基金会项目(K0601902) （K0601902）
广东省重大神经疾病诊治研究重点实验室(2020B1212060017) （2020B1212060017）
广东省神经系统疾病临床医学研究中心(2020B1111170002) （2020B1111170002）
华南神经疾病早期干预及功能修复研究国际联合研究中心(2015B050501003、2020A0505020004) （2015B050501003、2020A0505020004）
广东省神经系统重大疾病诊治工程技术研究中心、广东省神经系统重大疾病诊治转化医学创新平台和广州市神经系统重大疾病临床医学研究与转化中心项目(201604020010) （201604020010）
