北华大学学报（自然科学版）2025，Vol.26Issue(3)：311-316,6.DOI:10.11713/j.issn.1009-4822.2025.03.005
五味子根茎叶果多糖镇静催眠及抗焦虑作用
Sedative-hypnotic and Anxiolytic Effects of Polysaccharides from Root,Stem,Leaf and Fruit of Schisandra chinensis
摘要
Abstract
Objective Comparison of sedative,hypnotic and anxiolytic effects of Schisandra chinensis root,stem,leaf and fruit polysaccharides by behavioural tests in mice.Methods To detect the effects of Schisandra chinensis root,stem,leaf and fruit polysaccharides on voluntary activity,sleep rate,sleep duration and behavioral studies in the elevated plus maze and elevated zero maze in mice.Results In the sedative test,root,stem and fruit polysaccharides showed a good sedative effect.In the hypnotic test,root,stem,leaf and fruit polysaccharides demonstrated some hypnotic effect,with the effect of stem and fruit polysaccharides being stronger,followed by root polysaccharide,and lastly leaf polysaccharide.In the anxiolytic test,root,stem,leaf and fruit polysaccharides exhibited a good anxiolytic effect,with the effect of root polysaccharide being stronger,followed by stem polysaccharide,and lastly fruit polysaccharide.Conclusion Polysaccharides from the root,stem,leaf and fruit of Schisandra chinensis exhibit sedative,hypnotic and anxiolytic effects,with the stem and fruit polysaccharides demonstrating more significant effects.关键词
五味子/多糖/镇静/催眠/抗焦虑Key words
Schisandra chinensis/polysaccharides/sedative/hypnotic/anxiolytic分类
医药卫生引用本文复制引用
孙晓萌,李贺,陈红旭,吴诗卉,王欣,姜郁昕,高庆卓,邢昕雨,孙靖辉,王春梅..五味子根茎叶果多糖镇静催眠及抗焦虑作用[J].北华大学学报（自然科学版）,2025,26(3):311-316,6.基金项目
吉林省自然科学基金项目(20240305076YY,YDZJ202301ZYTS152). （20240305076YY,YDZJ202301ZYTS152）
