磁共振成像2025，Vol.16Issue(4)：93-98,6.DOI:10.12015/issn.1674-8034.2025.04.014
基于MRI影像组学预测腰椎间盘突出症针刺康复治疗临床疗效的初步探讨
Preliminary exploration of predicting clinical efficacy after acupuncture and rehabilitation therapy for lumbar disc herniation based on Radiomics Features of MRI
摘要
Abstract
Objective:To explore the value of an radiomics model based on MRI transverse axial plain scan in predicting the clinical efficacy of acupuncture and moxibustion rehabilitation therapy for lumbar disc herniation(LDH).Materials and Methods:A retrospective analysis was conducted on 155 LDH patients who had completed one courses of acupuncture and moxibustion rehabilitation treatment in hospital(102 cases were effective and 53 cases were ineffective).In R software,the patients were divided into a training set(n=108)and a testing set(n=47)using the sample function at a ratio of 7∶3.For each patient,851 radiomics features were extracted using 3D-Slicer software based on the pre-treatment magnetic resonance T2WI transverse axial image.After removing redundant features using Pearson or Spearman correlation analysis,the least absolute shrinkage and selection operator(LASSO)regression analysis was used to further reduce the dimensionality of the features and construct the model.The receiver operating characteristic(ROC)curve was applied to the training and testing sets to validate the model and evaluate the efficacy of radiomics features in predicting the clinical efficacy of acupuncture rehabilitation therapy for LDH.Results:After feature selection,7 radiomics features were used to construct a clinical efficacy prediction model for LDH acupuncture and moxibustion rehabilitation therapy.The area under the ROC curve(AUC)of the prediction model in the training set was 0.862[95%confidence interval(CI):0.789 to 0.935],with sensitivity and specificity of 82.5%and 75.0%,respectively;the AUC of the test set was 0.887(95%CI:0.773 to 0.989),with sensitivity and specificity of 92.3%and 79.4%,respectively.Conclusions:Based on the MRI axial imaging-based radiomics model,it exhibits excellent predictive performance for the clinical efficacy of acupuncture and rehabilitation therapy for LDH,serving as a robust basis for clinical decision-making.关键词
腰椎间盘突出症/针刺/康复治疗/磁共振成像/影像组学/疗效预测Key words
lumbar disc herniation/acupuncture/rehabilitation therapy/magnetic resonance imaging/radiomics/efficacy prediction分类
临床医学引用本文复制引用
刘荣,肖利,蒯林,武朦,韩超..基于MRI影像组学预测腰椎间盘突出症针刺康复治疗临床疗效的初步探讨[J].磁共振成像,2025,16(4):93-98,6.基金项目
Chengdu University of Traditional Chinese Medicine's"Xinglin Scholars"Discipline Talent Research Enhancement Plan(No.XJ2023022901). 成都中医药大学"杏林学者"学科人才科研提升计划项目(编号:XJ2023022901) （No.XJ2023022901）
