磁共振成像2025，Vol.16Issue(4)：108-113,6.DOI:10.12015/issn.1674-8034.2025.04.017
定量磁共振成像技术在帕金森病诊断中的研究进展
Research progress of quantitative magnetic resonance technique in the diagnosis of Parkinson's disease
摘要
Abstract
Parkinson's disease(PD)is the second most common neurological illness among middle-aged and elderly persons worldwide.In the early stages of the disease,it may only manifest as a slight tremor in the hands,making it easy to overlook;however,as the disease progresses,the patient's walking,thinking,sleeping,and so on will be affected,and eventually,he or she will be unable to care for himself or herself due to the inability to move around and become bedridden for an extended period of time.As a result,correct disease identification at an early stage can lead to better therapy,reduce disease progression,and improve prognosis.Quantitative MRI approaches can give non-invasive information on neuronal activity and metabolite changes in PD brain tissue,as well as the underlying biological characteristics of the disorders.In this article,we will look at how quantitative MRI techniques can aid with early PD diagnosis,lesion evaluation,treatment,and prognosis in clinical practice.关键词
帕金森病/磁共振成像/定量技术/化学交换饱和转移成像/神经黑色素成像Key words
Parkinson's disease/magnetic resonance imaging/quantitative techniques/chemical exchange saturation transfer/neuromelanin imaging分类
临床医学引用本文复制引用
李明龙,李祥林,刘苗苗,郭蓉,宁洪宇,徐璐梦,刘泉源..定量磁共振成像技术在帕金森病诊断中的研究进展[J].磁共振成像,2025,16(4):108-113,6.基金项目
National Natural Science Foundation of China(No.62176181) （No.62176181）
Shandong Provincial Natural Science Foundation(No.ZR2022MH118). 国家自然科学基金项目(编号:62176181) （No.ZR2022MH118）
山东省自然科学基金项目(编号:ZR2022MH118) （编号:ZR2022MH118）
