磁共振成像2025，Vol.16Issue(4)：114-119,138,7.DOI:10.12015/issn.1674-8034.2025.04.018
伴中央颞区棘波自限性癫痫功能连接研究进展
Research progress of Functional Connectivity in self-limited epilepsy with centrotemporal spikes
摘要
Abstract
Self-limited epilepsy with centrotemporal spikes(SeLECTS)is the most common age-dependent,self-limited focal epilepsy of childhood,characterised by interictal centrotemporal(Rolandic)spikes on the EEG.Although SeLECTS is considered self-limiting,some children have cognitive deficits in language,reading,visuospatial,executive function and attention.These deficits may be related to abnormalities in functional connectivity(FC),which can be paradoxically increased and decreased in different brain regions at the same time.This paper briefly introduces common functional connectivity research methods,summarises the strengths and weaknesses of these methods,and also summarises the research progress of FC in SeLECTS over the past years,with the aim of exploring the potential of FC as a biomarker for predicting cognitive and seizure outcomes.关键词
伴中央颞区棘波自限性癫痫/Rolandic癫痫/磁共振成像/功能磁共振成像/脑网络/功能连接Key words
self-limited epilepsy with centrotemporal spikes/Rolandic epilepsy/magnetic resonance imaging/functional magnetic resonance imaging/brain network/functional connectivity分类
临床医学引用本文复制引用
顾晓瑜,张家仁,宋林峰,王俊君,江林..伴中央颞区棘波自限性癫痫功能连接研究进展[J].磁共振成像,2025,16(4):114-119,138,7.基金项目
National Natural Science Foundation of China(No.82160328). 国家自然科学基金项目(编号:82160328) （No.82160328）
