结直肠肛门外科2025，Vol.31Issue(2)：133-137,5.DOI:10.19668/j.cnki.issn1674-0491.2025.02.008
腹腔镜结直肠癌根治术后患者静脉血栓栓塞症的发生情况及相关影响因素分析
Incidence and influencing factors of venous thromboembolism after laparoscopic radical re-section for colorectal cancer
摘要
Abstract
Objectives To analyze the incidence and influencing factors of venous thromboembolism(VTE)in patients un-dergoing laparoscopic radical resection for colorectal cancer(CRC).Methods A total of 140 CRC patients who underwent laparoscopic radical resection at Changshu No.2 People's Hospital from June 2021 to June 2024 were enrolled.VTE oc-currence within 2 weeks postoperatively was recorded.Patients were divided into VTE and non-VTE groups based on VTE status.Caprini score(assessed within 24 hours postoperatively)and clinical parameters were compared between groups.Results Among 140 patients,26(18.6％)developed VTE,including 25 cases of the deep vein thrombosis of lower extremities and 1 case of pulmonary embolism.The median Caprini score in the VTE group(n=26)was 4(IQR,3-4),significantly higher than that in the non-VTE group[n=114;median:2(IQR,2-2)](P＜0.05).Compared to the non-VTE group,the VTE group had older age,higher body mass index(BMI),higher preoperative D-dimer level,higher preop-erative plasma viscosity level,longer operative time,and longer postoperative immobilization time(P＜0.05).No signifi-cant differences were observed in sex ratio,Tumor-Node-Metastasis stage,preoperative radiotherapy,preoperative chemo-therapy,preoperative platelet count,preoperative fibrinogen level,preoperative prothrombin time,blood transfusion his-tory,prior VTE history,atherosclerotic disease history,postoperative anastomotic leakage,or postoperative bowel obstruc-tion(P＞0.05).Conclusion VTE incidence is notable after laparoscopic radical resection for CRC.Patients with VTE ex-hibit older age,higher BMI,higher preoperative D-dimer level,higher preoperative plasma viscosity level,longer operative time,and longer postoperative immobilization time compared to non-VTE patients.关键词
结直肠癌/腹腔镜根治术/静脉血栓栓塞症/影响因素Key words
colorectal cancer/laparoscopic radical resection/venous thromboembolism/influencing factors分类
临床医学引用本文复制引用
沈成龙,周放,刘海晨,石志良,郭健,杨逸,侍新宇,倪明良,周国强..腹腔镜结直肠癌根治术后患者静脉血栓栓塞症的发生情况及相关影响因素分析[J].结直肠肛门外科,2025,31(2):133-137,5.基金项目
常熟市科技计划(关键核心技术攻关—社会发展)项目(CS202313) （关键核心技术攻关—社会发展）
