动物医学进展2025,Vol.46Issue(6):110-118,9.
基于代谢组学的中兽药抗炎作用机制研究进展
Progress on the Anti-inflammatory Mechanisms of Traditional Chinese Veterinary Drugs Based on Metabolomics
摘要
Abstract
Metabolomics is a new branch of systematic biology after genomics,transcriptomics and pro-teomics.Metabonomics's unique view of the whole and dynamic view of organism coincides with the holis-tic view of TCM theory,therefore,it can be used as an effective tool for finding disease biomarkers and ex-ploring the complex effect relationship between life system and drugs.A large number of studies have shown that Chinese veterinary drugs have certain inhibitory effects on inflammatory reaction,but the anti-inflammatory mechanism needs further verification.Based on the metabolomics technology,the pharmaco-dynamic mechanism of Chinese veterinary drugs is discussed,and the potential biomarkers and therapeutic mechanisms are studied,more in line with the overall concept of Chinese medicine.This article reviews the practice of metabolomics-based approaches to the anti-inflammatory mechanism of traditional Chinese vet-erinary drugs,and looks forward to the future development of metabolomics.关键词
代谢组学/中兽药/抗炎机制Key words
Chinese veterinary drug/Metabolomics/Anti-inflammatory mechanism分类
农业科技引用本文复制引用
李晓蝶,潘诗琴,闵婷玉,王鲁,程振涛,欧德渊,宋旭琴,杨剑..基于代谢组学的中兽药抗炎作用机制研究进展[J].动物医学进展,2025,46(6):110-118,9.基金项目
贵州省基础研究(自然科学)项目(黔科合基础-ZK[2022]一般129) (自然科学)
国家自然科学基金项目(32202854) (32202854)
贵州省普通高等学校青年科技人才成长项目(黔教合KY字[2022]151号) (黔教合KY字[2022]151号)