动物医学进展2025，Vol.46Issue(6)：119-124,6.
他非诺喹治疗动物巴贝斯虫病
Tafenoquine in the Treatment of Babesiosis in Animals
摘要
Abstract
Babesiosis is a tick-borne protozoan malady instigated by parasites of the genus Babesia,predomi-nantly transmitted through the hematophagous activity of infected ticks.Clinical manifestations of babesio-sis encompass pyrexia,icterus,hemolytic anemia,and hemoglobinuria,with severe instances potentially cul-minating in mortality.The therapeutic regimen for babesiosis typically entails the administration of antipro-tozoal drugs,such as imidocarb dipropionate,diminazen aceturate,and trypan blue via intramuscular injec-tions,or oral antimicrobials including artemisinin and doxycycline.The prescribed treatment duration gen-erally spans 7-10 days.Tafenoquine,an innovative antimalarial agent,has also demonstrated efficacy in trea-ting babesiosis.Empirical studies on tafenoquine have elucidated its capacity to surmount extant issues of chemoresistance associated with babesiosis therapies,alongside confirming its favorable safety profile.This discourse endeavors to delineate the extant therapeutic strategies for babesiosis and the advancements in tafenoquine research,thereby furnishing a comprehensive reference for enhanced prophylaxis and manage-ment of Babesia-induced pathologies.关键词
巴贝斯虫病/药物治疗/他非诺喹Key words
Babesiosis/Drug treatment/Tafenoquine分类
畜牧业引用本文复制引用
王奕博,汲生威,金春梅..他非诺喹治疗动物巴贝斯虫病[J].动物医学进展,2025,46(6):119-124,6.基金项目
国家自然科学基金项目(32060807) （32060807）
