分析化学2025，Vol.53Issue(4)：547-560,14.DOI:10.19756/j.issn.0253-3820.241350
金属有机框架-适配体传感器检测药食同源物质中污染物的研究进展
Research Progress of Metal-Organic Frameworks-Aptasensors for Detection of Contaminants in Food and Medicine Homology Substances
摘要
Abstract
In recent years,the market share of food and medicine homology substances has continued to grow,and various types of contamination issues have become the focus of attention both inside and outside the industry.The contamination not only affects the original medicinal quality,but also leads to the accumulation of toxic substances in the human body,causing acute and chronic severe hazards such as vomiting,poisoning and cancer.Therefore,the development of biosensors that can conveniently,accurately and sensitively detect various pollutants in food and medicine homology substances has become a research hotspot.Aptasensors based on metal-organic frameworks(MOFs)with advantages such as strong specificity,rapid response and simple operation,have been widely used in detection of various pollutants.This review focused on the research progress of aptasensors based on MOFs for detection of food and medicine homology contamination in the past few years,and provided a detailed comparison and analysis for detection of chemical pollutants(such as pesticide residues,heavy metal residues,mycotoxins,etc.)and microbial contamination in food and medicine homology substances.Besides,the development trend and possible challenges of MOFs aptasensors in detection of food and medicine homology substances in the future were discussed,which was anticipated to provide a reference for the development of new MOFs aptasensors.关键词
药食同源/金属有机框架/适配体传感器/污染物/评述Key words
Food and medicine homology/Metal-organic frameworks/Aptasensors/Contaminants/Review引用本文复制引用
郭星,田金举,唐晓珍,王晓玥,宋娜,王金娥,朱超..金属有机框架-适配体传感器检测药食同源物质中污染物的研究进展[J].分析化学,2025,53(4):547-560,14.基金项目
国家自然科学基金(No.32071392)、山东省自然科学基金(No.ZR2023QB302)和德州学院科研启动基金项目(Nos.2022xjrc203,2024xjrc111)资助. Supported by the National Natural Science Foundation of China(No.32071392),the Natural Science Foundation of Shandong Province(No.ZR2023QB302)and the Scientific Research Startup Foundation Project of Dezhou University(Nos.2022xjrc203,2024xjrc111). （No.32071392）
