影像科学与光化学2025，Vol.43Issue(3)：13-18,6.DOI:10.7517/issn.1674-0475.2025.03.02
老年结肠癌CT增强扫描对EMVI的诊断及术后PFS预测价值
Value of Enhanced CT Scan in the Diagnosis of EMVI and Prediction of Postoperative PFS in Elderly Patients with Colon Cancer
摘要
Abstract
Objective:To investigate the diagnostic value of enhanced CT scan in elderly patients with extramural venous invasion(EMVI)and to analyze its predictive value for postoperative progression-free survival(PFS).Methods:The clinical data of 97 elderly patients with colon cancer admitted to our hospital from October 2018 to September 2022 were reviewed.The value of enhanced CT scan in the diagnosis of EMVI was analyzed based on postoperative pathological diagnosis.Cox proportional hazard regression model and Kaplan-Meier method were used to analyze the relationship between EMVI and PFS.Results:Compared with EMVI negative patients,the proportion of tumor non-uniform enhancement in venous phase,tumor venous and arterial phase CT value of EMVI positive elderly colon cancer patients were higher(P＜0.05).The sensitivity and specificity of enhanced CT scan in diagnosing EMVI were 78.95％and 74.58％,respectively.The coincidence rate between enhanced CT scan and pathological results was 76.29％,and the consistency between enhanced CT scan and pathological results was good(Kappa=0.518,P＜0.001).Follow-up showed progression-free survival in 72 patients(74.23％).Kaplan-Meier survival curve analysis showed that the cumulative progression-free survival rate of EMVI-positive patients was lower than that of EMVI-negative patients(Logrank x2=11.302,P=0.001).Multivariate Cox regression analysis showed that uneven enhancement in venous stage,positive CT value and EMVI in venous stage and arterial stage were independent risk factors for elderly colon cancer PFS(P＜0.05).Conclusion:Enhanced CT scan is helpful for the diagnosis of EMVI in elderly patients with colon cancer,and EMVI positive is an independent risk factor affecting progression-free survival in elderly patients with colon cancer,and has certain value in predicting progression-free survival.关键词
结肠癌/肠外静脉侵犯/CT增强扫描/无进展生存期/老年Key words
colon cancer/extramural venous invasion/enhanced CT scan/progression-free survival/elderly分类
临床医学引用本文复制引用
衣家奇,张楠,王海阳,王磊..老年结肠癌CT增强扫描对EMVI的诊断及术后PFS预测价值[J].影像科学与光化学,2025,43(3):13-18,6.基金项目
黑龙江省自然科学基金项目(LK2022H023). （LK2022H023）
