影像科学与光化学2025，Vol.43Issue(3)：19-24,6.DOI:10.7517/issn.1674-0475.2025.03.03
C-TIRADS超声指南联合超微血管成像技术对甲状腺结节性质的诊断价值
Diagnostic Value of C-TIRADS Guidelines Combined with Superb Micro-vas-cular Imaging in Characterization of Thyroid Nodules
摘要
Abstract
Objective:To evaluate the diagnostic value of Chinese guidelines for ultrasound malignant risk stratification of thyroid nodules(C-TIRADS)combined with superb micro-vascular imaging(SMI).Methods:A total of 116 patients with thyroid nodules were selected from the First Affiliated Hospital of Hebei North University after fine needle puncture or pathological diagnosis.All patients received two-dimensional gray scale ultrasound,color ultrasound,and SMI examination.Based on these examination results,C-TIRADS classification and SMI classification were performed.The diagnostic efficiency of C-TIRADS classification and SMI classification for malignant thyroid nodules was analyzed by receiver operating characteristic(ROC)curve.Results:141 thyroid nodules were detected in 116 patients,including 59 malignant nodules(41.84％)and 82 benign nodules(58.16％).C-TIRADS classification was used to classify thyroid nodules into malignant risk categories of 5,22,13,22,65 and 14 thyroid nodules in categories 2,3,4A,4B,4C and 5,respectively,with malignant rates of 0,0,7.69％,9.09％,66.15％and 92.85％.The classification of C-TIRADS was consistent with the pathological results(Kappa=0.625,P＜0.001).There were 10,45,28,29,29 malignant risk categories of thyroid nodule ficat＜0.001).There were 10,45,28,29,29 malignant risk categories of thyroid nodule fication of C-TIRADS was consistent relatively high consistency between SMI classification and pathological results(Kappa=0.606,P＜0.001).The sensitivity,specificity and AUC(95％CI)of C-TIRADS in the diagnosis of malignant thyroid nodules were 94.92％,71.95％and 0.868(0.801～0.919),respectively,and SMI were 76.27％,84.15％and 0.860(0.792～0.913),respectively.The combined diagnosis of C-TIRADS and SMI was 94.92％,82.93％and 0.937(0.883～0.971),respectively.Both specificity and AUC were improved compared with single application,and the diagnostic efficiency of combined application was higher than that of single application(Z=4.103,3.501,P＜0.001).Conclusion:C-TIRADS classification and SMI classification of thyroid nodules have high consistency with pathological diagnosis results.The combined diagnosis of C-TIRADS classification and SMI classification is helpful to improve the diagnostic efficiency of malignant thyroid nodules.关键词
甲状腺结节/超声恶性危险分层中国指南/超微血管成像技术/诊断Key words
thyroid nodules/C-TIRADS/superb micro-vascular imaging/diagnosis分类
临床医学引用本文复制引用
刘晓城,李卫天,李永,赵御森,许园博,马永青,李传贵,杨飞..C-TIRADS超声指南联合超微血管成像技术对甲状腺结节性质的诊断价值[J].影像科学与光化学,2025,43(3):19-24,6.基金项目
2023年度河北省医学科学研究课题计划(20231439). （20231439）
