赣南医科大学学报2025，Vol.45Issue(3)：225-231,7.DOI:10.3969/j.issn.1001-5779.2025.03.003
斑马鱼模型在甲状腺癌研究中的优势、进展与前景
Advantages,progress and prospects of the zebrafish model in the research of thyroid cancer
摘要
Abstract
Thyroid cancer(TC)is a common endocrine malignancy with a complex pathogenesis difficult to replicate in vitro models.In recent years,the zebrafish model has emerged as a powerful tool in cancer research,due to its unique advantages such as small size,transparent embryos and larvae,and short growth cycle.Its application in tumor research has become increasingly widespread.In the study of TC,researchers have found that zebrafish can effectively simulate the occurrence and development of human TC,thereby providing a strong basis for investigating the molecular mechanisms of TC and identifying new therapeutic targets.This article briefly reviews the development of zebrafish model in clinical research and their advantages in cancer research,with a focus on the results obtained from the use of zebrafish model in TC studies,and discuss the future direction of zebrafish research in the field of TC.关键词
甲状腺癌/斑马鱼/动物模型/药物筛选Key words
Thyroid cancer/Zebrafish/Animal model/Drug screening分类
医药卫生引用本文复制引用
黄宏毅,黄雪梅,魏海燕,陈芳,何明杰,彭璐璐,徐帆,许荣..斑马鱼模型在甲状腺癌研究中的优势、进展与前景[J].赣南医科大学学报,2025,45(3):225-231,7.基金项目
江西省教育厅科学技术研究项目(GJJ2201434) （GJJ2201434）
江西省卫生健康委员会科技计划项目(202210870) （202210870）
