广州医药2025，Vol.56Issue(4)：523-528,6.DOI:10.20223/j.cnki.1000-8535.2025.04.013
达泊西汀联合达克罗宁胶浆治疗早泄的临床研究
Clinical study on the treatment of premature ejaculation with dapoxetine combined with dacronine mucilage
张同殿 1谢明亮 1赵守国 1候方方 1郭丙毅 1孔佳2
作者信息
- 1. 聊城市人民医院男科(山东 聊城 252000)
- 2. 聊城市人民医院肾内科(山东 聊城 252000)
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of dapoxetine hydrochloride combined with dclonine mucilage in the treatment of premature ejaculation.Methods A total of 146 patients from andrology department with premature ejaculation were selected and randomly divided into control group and research group.The control group was treated with dapoxetine alone,while the research group was treated with dapoxetine combined with dacronine mucilage.The research group was divided into high sensitivity group and normal sensitivity group.The indexes related to premature ejaculation were recorded before treatment and 8 weeks after treatment.Results After treatment,intravaginal ejaculatory latency time(IELT),Premature Ejaculation Diagnosis Tool(PEDT)and Q6+Q7 of the index of premature ejaculation(IPE)in control group were(4.68±2.79),(9.52±2.14)and(6.48±1.30),respectively,while IELT,PEDT and Q6+Q7 in research group were(6.09±3.09),(7.52±1.92)and(7.85±1.36),respectively.The relevant indexes in all groups were significantly improved compared with those before treatment(P＜0.05),and the improvement of all indexes in research group was better than that in control group(P＜0.05).After treatment,IELT,PEDT and Q6+Q7 in the highly sensitivity group were(6.76±2.99),(6.84±1.53)and(8.16±1.10),respectively,while IELT,PEDT and Q6+Q7 in the normal sensitivity group were(5.13±3.02),(8.50±2.03)and(7.40±1.59),respectively.The improvement of all indexes in the high sensitivity group was better than that in the normal sensitivity group(P＜0.05).The total effective rate of the control group and the research group was 69.86%(51/73)and 84.93%(62/73),respectively.The therapeutic effect of the research group was significantly better than that of the control group(P＜0.05).The total effective rate of the high sensitivity group and the normal sensitivity group was 93.02%(40/43)and 73.33%(22/30),respectively.The therapeutic effect of the high sensitivity group was significantly better than that of the normal sensitivity group(P＜0.05).Conclusions Dapoxetine combined with dacronine mucilage has significant effect in the treatment of premature ejaculation,and the patients with high sensitivity of penile head will benefit more from combined dacronine mucilage therapy.关键词
盐酸达泊西汀/达克罗宁胶浆/阴茎头敏感度/早泄Key words
dapoxetine/dacronine mucilage/sensitivity of penile head/premature ejaculation引用本文复制引用
张同殿,谢明亮,赵守国,候方方,郭丙毅,孔佳..达泊西汀联合达克罗宁胶浆治疗早泄的临床研究[J].广州医药,2025,56(4):523-528,6.
