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瑞马唑仑联合氯胺酮对行面部整形手术患者循环呼吸、术后应激反应及炎症水平的影响

赖丹 成姝姝 雷文丽 杜淼

保健医学研究与实践2024,Vol.21Issue(Z2):187-190,4.
保健医学研究与实践2024,Vol.21Issue(Z2):187-190,4.DOI:10.11986/j.issn.1673-873X.2024.S2.41

瑞马唑仑联合氯胺酮对行面部整形手术患者循环呼吸、术后应激反应及炎症水平的影响

Impact of remimazolam combined with ketamine on circulatory-respiratory function,postoperative stress response,and inflammatory levels in patients undergoing facial plastic surgery

赖丹 1成姝姝 2雷文丽 1杜淼1

作者信息

  • 1. 四川省成都高新米兰柏羽医学美容医院,成都 610000
  • 2. 四川省成都新华医院,成都 610000
  • 折叠

摘要

Abstract

Objective To investigate the effects of remimazolam combined with ketamine on circulatory-respiratory function,postoperative stress response,and inflammatory levels in patients undergoing facial plastic surgery.Methods One hundred patients undergoing facial plastic surgery in the Department of Anesthesiology from March 2021 to March 2024 were selected and divided into an observation group and a control group using the random number table method,with 50 cases each.The control group received propofol combined with remifentanil for anesthesia,while the observation group received remimazo-lam combined with ketamine.Circulatory-respiratory parameters,postoperative stress response markers[cortisol(Cor),al-dosterone(ALD),angiotensin Ⅱ(Ang-Ⅱ)],and inflammatory levels were compared between the two groups.Results Post-anesthesia,the observation group exhibited significantly higher circulatory-respiratory indices and lower inflammatory levels,Cor,ALD,and Ang-Ⅱ levels compared to the control group(P<0.05).Conclusion The combination of remima-zolam and ketamine for anesthesia in facial plastic surgery effectively promotes circulatory-respiratory function,mitigates postoperative stress responses,and reduces inflammatory levels.

关键词

瑞马唑仑/面部整形手术/氯胺酮/循环呼吸/应激反应

Key words

Remimazolam/Facial plastic surgery/Ketamine/Circulatory-respiratory function/Stress response

分类

医药卫生

引用本文复制引用

赖丹,成姝姝,雷文丽,杜淼..瑞马唑仑联合氯胺酮对行面部整形手术患者循环呼吸、术后应激反应及炎症水平的影响[J].保健医学研究与实践,2024,21(Z2):187-190,4.

保健医学研究与实践

OACSTPCD

1673-873X

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