国际神经病学神经外科学杂志2025，Vol.52Issue(2)：57-61,5.DOI:10.16636/j.cnki.jinn.1673-2642.2025.02.009
血浆致动脉硬化指数对急性缺血性脑卒中患者神经功能缺损程度的预测价值
Value of atherogenic index of plasma in predicting the degree of neurological impairment in patients with acute ischemic stroke
摘要
Abstract
Objective To investigate the value of atherogenic index of plasma(AIP)in predicting the degree of neurological impairment in patients with acute ischemic stroke(AIS).Methods Clinical data were collected from 305 patients with AIS who were hospitalized in Department of Neurology,Heze Municipal Hospital,from January 2022 to May 2024.And according to the National Institutes of Health Stroke Scale(NIHSS)score on admission,they were divided into normal group(86 patients with an NIHSS score of 0),mild group(131 patients with an NIHSS score of≥1 and≤4),and moderate or severe group(88 patients with an NIHSS score of>4).Related risk factors were compared among the three groups,and the correlations between AIP and other indicators were analyzed.The receiver operator characteristic(ROC)curve was used to investigate the value of AIP in predicting the degree of neurological impairment in patients with AIS.Results There were significant differences among the three groups in fasting blood glucose,triglyceride,high-density lipoprotein cholesterol,low-density lipoprotein cholesterol,total cholesterol,and AIP(P<0.05).AIP was positively correlated with NIHSS score,fasting blood glucose,triglyceride,low-density lipoprotein cholesterol,and total cholesterol(P<0.05),and it was negatively correlated with high-density lipoprotein cholesterol(P<0.05).The ROC curve analysis showed that AIP had an optimal cut-off value of 2.03 in predicting neurological impairment(NIHSS score≥1)in patients with AIS(P<0.001),with a sensitivity of 72.1%and a specificity of 66.3%.Conclusions AIP is positively correlated with the degree of neurological impairment in patients with AIS and has a certain predictive value for neurological impairment.关键词
急性缺血性脑卒中/血浆致动脉硬化指数/神经功能缺损Key words
acute ischemic stroke/atherogenic index of plasma/neurological impairment分类
临床医学引用本文复制引用
提衍丽,王文文,黄媛媛,王丽娜..血浆致动脉硬化指数对急性缺血性脑卒中患者神经功能缺损程度的预测价值[J].国际神经病学神经外科学杂志,2025,52(2):57-61,5.基金项目
菏泽市立医院科技项目(2024YN23). （2024YN23）
