摘要
Abstract
Objective To investigate the clinical effect of repetitive transcranial magnetic stimulation(rTMS)in the treatment of sleep disorders in patients with benign paroxysmal positional vertigo(BPPV).Methods A total of 270 patients with BPPV and sleep disorders who were treated in Shanghai Municipal Hospital of Traditional Chinese Medicine were enrolled as subjects and were randomly divided into control group with 134 patients and observation group with 136 patients.The patients in both groups were given canalith repositioning maneuver combined with betahistine,and in addition,those in the observation group were given rTMS;the course of treatment was 4 weeks for both groups.Before and after treatment,Pittsburgh Sleep Quality Scale(PSQI)was used to assess the sleep status of patients,Hamilton Depression Scale-17(HAMD-17)was used to evaluate the degree of depression,and Dizziness Handicap Inventory(DHI)was used to assess the degree of dizziness.Overall treatment response was compared between the two groups.Results Before treatment,there were no significant differences in PSQI,HAMD,and DHI scores between the two groups(P>0.05).After treatment,both groups had significant reductions in PSQI,HAMD-17,and DHI scores,and the observation group had significantly lower PSQI,HAMD,and DHI scores than the control group(P<0.05).The observation group had a significantly higher overall response rate than the control group(86.8%vs 53.0%,P<0.05).Conclusions rTMS combined with canalith repositioning maneuver and betahistine can effectively improve sleep disorders and depression in BPPV patients,with a better clinical effect than canalith repositioning maneuver combined with betahistine.关键词
良性阵发性位置性眩晕/重复经颅磁刺激/睡眠障碍/抑郁Key words
benign paroxysmal positional vertigo/repetitive transcranial magnetic stimulation/sleep disorder/depression分类
医药卫生
