中医药导报2025，Vol.31Issue(4)：77-82,88,7.DOI:10.13862/j.cn43-1446/r.2025.04.013
参蝎止痛胶囊质量标准研究
Research on Quality Standard of Shenxie Zhitong Capsules(参蝎止痛胶囊)
摘要
Abstract
Objective:To establish a quality standard of Shenxie Zhitong Capsules(参蝎止痛胶囊).Methods:Thin-Layer Chromatography(TLC)was used to identify Sanqi(Notoginseng Radix Et Rhizoma),Quanxie(Scorpio)and Tubiechong(Eupolyphaga Steleophaga).High Performance Liquid Chromatography(HPLC)was used to determine the contents of Ginsenoside Rg1,Notoginsenoside R1,and Ginsenoside Rb1.Results:The TLC chromatogram of test solution showed characteristic spots of Sanqi(Notoginseng Radix Et Rhizoma),Quanxie(Scorpio)and Tubiechong(Eupolyphaga Steleophaga).The spots were clear and the negative reference had no interference.Compounds being examined showed high separation and good specificity in HPLC chromatogram,methodological inspections met requirements of content determination.Conclusion:The methods of TLC and HPLC had advantages of process simplicity and good repeatability that can be used to establish quality standard of Shenxie Zhitong Capsules.关键词
参蝎止痛胶囊/质量标准/薄层色谱法/高效液相色谱法/含量测定Key words
Shenxie Zhitong Capsules/quality standard/thin-layer chromatography/high performance liquid chromatography/content determination分类
医药卫生引用本文复制引用
沈婷婷,陈清光,刘瑾,张建伟..参蝎止痛胶囊质量标准研究[J].中医药导报,2025,31(4):77-82,88,7.基金项目
上海市2022年度"科技创新行动计划"生物医药科技支撑专项项目(22S21900400) （22S21900400）
