中医药导报2025,Vol.31Issue(4):102-108,7.DOI:10.13862/j.cn43-1446/r.2025.04.016
蒙药肋柱花化学成分、药理作用及临床应用研究进展
Research Advances in Chemical Constituents,Pharmacological Effects,and Clinical Applications of Lomatogonium Rotatum(Mongolian Medicine)
摘要
Abstract
Lomatogonium rotatum(Mongolian name:Habirigen-Yidagda),a dried whole herb of Lomatogonium rotatum(Gentianaceae),is a traditional Mongolian medicinal plant widely used to treat biliary disorders,jaundice,"Xieri"fever(a heat-related syndrome in Mongolian medicine),and hepatobiliary inflammatory diseases.It is recognized for its effects in inhibiting"Xieri"(a pathological heat concept),reducing fever,healing wounds,and improving digestion.Based on a comprehensive review of domestic and international literature over the past two decades,the chemical constituents of L.rotatum primarily include flavonoids,xanthones,iridoids,triterpenoids,lignans,and fatty acids.Extracts of L.rotatum exhibit notable pharmacological activities,including anticancer,hepatoprotective,and antibacterial effects.Furthermore,its compound preparations,though limited in variety,have shown significant therapeutic potential in specific diseases.With in-depth exploration of its chemical composition,pharmacological properties,and clinical applications,L.rotatum and its compound formulations are expected to become distinctive ethnic medicines for treating tumors and hepatobiliary diseases,offering safe and effective clinical solutions while invigorating the inheritance and development of traditional medicine.关键词
肋柱花/蒙药/化学成分/药理作用/临床应用/综述Key words
Lomatogonium rotatum/Mongolian medicine/chemical constituents/pharmacological effects/clinical applications/review分类
医药卫生引用本文复制引用
黎龙,李晓磊,田景民,张慧文,王建业,李骁..蒙药肋柱花化学成分、药理作用及临床应用研究进展[J].中医药导报,2025,31(4):102-108,7.基金项目
内蒙古自治区教育科学规划课题项目(NGJGH2021314) (NGJGH2021314)
内蒙古医科大学青年领创团队项目(QNLC-2020054) (QNLC-2020054)
内蒙古医科大学面上项目(YKD2023MS075) (YKD2023MS075)