中医药导报2025，Vol.31Issue(4)：114-117,126,5.DOI:10.13862/j.cn43-1446/r.2025.04.018
天麻钩藤饮加减联合针刺对阴虚阳亢型高血压患者血压波动及臂踝脉搏波传导速度的影响
Effects of Modified Tianma Gouteng Decoction(天麻钩藤饮)Combined with Acupuncture on Blood Pressure Variability and Brachial-Ankle Pulse Wave Velocity in Hypertensive Patients with Yin Deficiency and Yang Hyperactivity
摘要
Abstract
Objective:To investigate the effects of modified Tianma Gouteng Decoction(天麻钩藤饮)combined with acupuncture on blood pressure variability and brachial-ankle pulse wave velocity(baPWV)in hypertensive patients with Yin deficiency and Yang hyperactivity.Methods:Sixty hypertensive patients admitted to the Department of Traditional Chinese Medicine at Hefei Third People's Hospital from January 2023 to January 2024 were randomly divided into a control group(30 cases)and an observation group(30 cases).The control group received conventional antihypertensive drugs,while the observation group was treated with modified Tianma Gouteng Decoction and acupuncture in addition to the control regimen.Blood pressure parameters[systolic blood pressure(SBP),diastolic blood pressure(DBP)],baPWV,blood pressure variability[24-hour mean SBP(MSBP),24-hour mean DBP(MDBP),24-hour SBP coefficient of variation(SBPCV),24-hour DBP coefficient of variation(DBPCV)],traditional Chinese medicine(TCM)syndrome scores,vascular endothelial growth factor(VEGF),and homocysteine(Hcy)were compared before and after treatment.The clinical efficacy aslo was compared between the two groups.Results:The total effective rate was 93.33%(28/30)in the observation group and 73.33%(22/30)in the control group,with a statistically significant difference(P<0.05).After treatment,both groups showed reductions in SBP,DBP,baPWV,24-hour MSBP,24-hour MDBP,24-hour SBPCV,24-hour DBPCV,TCM syndrome scores,and serum levels of VEGF and Hcy.Moreover,the observation group exhibited significantly lower values than the control group in all parameters(P<0.05).Conclusion:Modified Tianma Gouteng Decoction combined with acupuncture effectively reduces blood pressure,baPWV,and blood pressure variability in hypertensive patients with Yin deficiency and Yang hyperactivity.The therapeutic mechanism may be associated with downregulation of VEGF and Hcy levels.关键词
高血压/阴虚阳亢/天麻钩藤饮/针刺/血压波动/臂踝脉搏波传导速度Key words
hypertension/Yin deficiency and Yang hyperactivity/Tianma Gouteng Decoction/acupuncture/blood pressure variability/brachial-ankle pulse wave velocity分类
医药卫生引用本文复制引用
刘华丹,刘汉顺,黄春华,邢齐树,吴蓉..天麻钩藤饮加减联合针刺对阴虚阳亢型高血压患者血压波动及臂踝脉搏波传导速度的影响[J].中医药导报,2025,31(4):114-117,126,5.基金项目
合肥市中医药研究项目(HFSZYYYJ2024-3) （HFSZYYYJ2024-3）
