中医药导报2025，Vol.31Issue(4)：122-126,5.DOI:10.13862/j.cn43-1446/r.2025.04.020
七味疗疮解毒散穴位贴敷联合富血小板血浆凝胶治疗住院感染性压疮的临床研究
Clinical Study on Acupoint Application of Qiwei Liaochuang Jiedu Powder(七味疗疮解毒散)Combined with Platelet-Rich Plasma Gel in Treating Hospital-Acquired Infected Pressure Ulcers
摘要
Abstract
Objective:To evaluate the clinical efficacy of acupoint application of Qiwei Liaochuang Jiedu Powder(a seven-herb formula for ulcer detoxification)combined with platelet-rich plasma(PRP)gel in treating hospitalized patients with infected pressure ulcers.Methods:Ninety patients with stage Ⅲ-Ⅳ infected pressure ulcers were randomly divided into an observation group,Control group 1,and Control group 2(30 cases each).All groups received MEBO M oist Exposed Burn Ointment.Control group 1 additionally received PRP gel,Control group 2 received acupoint application of Qiwei Liaochuang Jiedu Powder,and the observation group received both interventions.Clinical efficacy,wound healing time,Vancouver Scar Scale(VSS)scores,bacterial clearance time,Pressure Ulcer Scale for Healing(PUSH)scores at 1 and 3 months,and serum levels of C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),and procalcitonin(PCT)were compared.Adverse reactions were recorded.Results:The observation group showed a total effective rate of 93.33%(28/30),significantly higher than 73.33%(22/30)in Control group 1 and 70.00%(21/30)in Control group 2(P<0.05).The observation group exhibited shorter wound healing time,lower VSS scores(P<0.05),and higher rates of bacterial clearance within<2 weeks compared to both control groups(P<0.05).PUSH scores at 1 and 3 months,as well as CRP,ESR,and PCT levels at 3 months,were significantly lower in the observation group(P<0.05).No significant difference in adverse reactions was observed among groups(P>0.05).Conclusion:The combination of Qiwei Liaochuang Jiedu Powder acupoint application and PRP gel effectively suppresses inflammatory progression,shortens bacterial clearance time,accelerates wound repair in infected pressure ulcers,and demonstrates favorable safety.关键词
感染性压疮/七味疗疮解毒散/穴位贴敷/富血小板血浆凝胶/美宝湿润烧伤膏/中西医结合/创面修复/临床研究Key words
infected pressure ulcers/Qiwei Liaochuang Jiedu Powder/acupoint application/platelet-rich plasma gel/MEBO Moist Exposed Burn Ointment/integrated traditional Chinese and Western medicine/wound healing/clinical study分类
医药卫生引用本文复制引用
唐培群,韩杰..七味疗疮解毒散穴位贴敷联合富血小板血浆凝胶治疗住院感染性压疮的临床研究[J].中医药导报,2025,31(4):122-126,5.基金项目
广西壮族自治区中医药管理局自筹经费科研课题(GXZYC20220506) （GXZYC20220506）
