保健医学研究与实践2025，Vol.22Issue(1)：93-101,9.DOI:10.11986/j.issn.1673-873X.2025.01.15
视频脑电图在儿童良性癫痫伴中央颞区棘波患儿中的应用效果
Application of video electroencephalography in children with benign epilepsy with centrotemporal spikes
摘要
Abstract
Objective To evaluate the clinical value of video electroencephalography(VEEG)in children with benign epilepsy with centrotemporal spikes(BECT)and provide evidence for diagnosis and treatment.Methods Clinical data from 107 BECT patients admitted to Baoji Maternal and Child Health Hospital from January 2021 to January 2024 were analyzed.VEEG parameters,including spike-wave index(SWI)and discharge localization,were recorded.Neurocognitive function was assessed using the Wechsler Intelligence Scale for Children-Fifth Edition(WISC-V),and behavioral performance was e-valuated with the Achenbach Child Behavior Checklist(CBCL).VEEG characteristics were compared across disease severity levels,treatment efficacy,and discharge localization,and their correlations with neurocognitive and behavioral outcomes were explored.Results Among 107 BECT patients,38(35.52%)had mild,42(39.25%)moderate,and 27(25.23%)severe disease.After anti-epileptic drugs and behavioral interventions,69(64.48%)were classified as effective responders and 38(35.52%)as non-responders.Seizure frequency(F=167.889)and duration(F=509.420)increased with disease severity(all P<0.05).The effective group showed significantly lower seizure frequency,shorter duration,and reduced SWI compared to the non-effective group(P<0.05).The severe group scored significantly lower in 5-subscale(verbal com-prehension,visual-spatial ability,fluid reasoning,working memory,processing speed)and total scores of WISC-V than the mild and moderate groups,and those in the moderate group were lower than those in the mild group(P<0.05).The scores of 5-subscale and total scores of WISC-V in the central group were higher than those in the combined group,and the scores of visual-spatial ability and fluid reasoning subscales in the temporal block group were higher than those in the combined group,with statistical significance(P<0.05).The 8-subscale(withdrawal,rule-breaking,aggression,social problems,attention deficits,thought problems,somatic complaints,and anxiety/depression)and total scores of behavioral problems module in the CBCL scale in the severe group were higher than those in the mild group and moderate group,and those in the moderate group were higher than those in the mild group,with statistical significance(P<0.05);the 8-subscale and total scores of behavioral problems module in CBCL scale in combined group were higher than those in central group and temporal group,and those in temporal group were higher than those in central group,with statistical significance(P<0.05).The total score of WISC-V was negatively correlated with SWI,seizure frequency,and duration(r=-0.414,-0.401,-0.340,all P<0.05);the total score of CBCL was positively correlated with SWI,seizure frequency,and duration(r=0.492,0.499,0.500,all P<0.05).Conclusion VEEG is critical for diagnosing BECT,assessing disease severity,and predicting prognosis.It provides essential support for clinical decision-making.关键词
伴中央颞区棘波儿童良性癫痫/视频脑电图/棘慢波放电指数/神经认知功能Key words
Benign epilepsy with centrotemporal spikes/Video electroencephalography/Spike-wave index/Neurocognitive function分类
医药卫生引用本文复制引用
张斌,李宏艳,胡春维,刘志华,杨惠婷,王灿军,冯西宁..视频脑电图在儿童良性癫痫伴中央颞区棘波患儿中的应用效果[J].保健医学研究与实践,2025,22(1):93-101,9.基金项目
陕西省重点研发计划项目(2018SF-243). （2018SF-243）
