保健医学研究与实践2025，Vol.22Issue(1)：138-143,6.DOI:10.11986/j.issn.1673-873X.2025.01.21
1型糖尿病患儿持续血糖监测与自我血糖监测评估血糖指标的一致性分析
Consistency analysis of glucose metrics between continuous glucose monitoring and self-monitoring of blood glucose in children with type 1 diabetes mellitus
摘要
Abstract
Objective To evaluate the consistency of glucose metrics obtained from self-monitoring of blood glucose(SMBG)and continuous glucose monitoring(CGM)in children with type 1 diabetes mellitus(T1 DM).Methods We retrospectively analyzed CGM and SMBG data from T1 DM children treated at Children's Hospital of Chongqing Medical University between November 2019 and September 2021.Consistency between CGM-and SMBG-derived glucose metrics was assessed using the Wilcoxon signed-rank test,Kendall's W coefficient,and Bland-Altman plots.Results Thirty-six paired SMBG and CGM datasets were included.No significant differences were found between the two methods in calculating time in range(TIR),time above range(TAR),time below range(TBR),mean blood glucose(MBG),or glucose variability(GV)of glucose(P>0.05).However,a significant difference was observed in largest amplitude of glucose excursions(LAGE)(P<0.05).Kendall's W analysis showed strong consistency for TIR and TBR(Kendall's W=0.77 and 0.73,respectively),and highly strong consistency for TAR,MBG,and GV(Kendall's W=0.83,0.89,and 0.90,respectively).Bland-Altman plots demonstrated good overall agreement between SMBG and CGM for TIR,TAR,TBR,MBG,and GV.Conclusion SMBG and CGM show high consistency in assessing glucose metrics including TIR,TAR,and TBR in children with T1 DM.For pediatric patients without access to CGM,SMBG can serve as a reliable alternative monitoring method.关键词
1 型糖尿病/自我血糖监测/持续葡萄糖监测/目标范围内时间/一致性Key words
Type 1 diabetes mellitus/Self-monitoring of blood glucose/Continuous glucose monitoring/Time in range/Con-sistency分类
医药卫生引用本文复制引用
谌业净,陈利平,刘晓琴,刘静,周娜,林琴,吴利平..1型糖尿病患儿持续血糖监测与自我血糖监测评估血糖指标的一致性分析[J].保健医学研究与实践,2025,22(1):138-143,6.基金项目
重庆市自然科学基金面上项目(CSTB2022NSCQ-MSX0131) （CSTB2022NSCQ-MSX0131）
重庆医科大学护理学院2023年院级科学研究项目一般项目(20230408) （20230408）
重庆市教委十四五重点学科支持项目(20240104). （20240104）
