广州化学2025，Vol.50Issue(2)：15-19,5.DOI:10.16560/j.cnki.gzhx.20250211
可见光介导苯乙烯和苯甲醛亲核加成制备仲醇
Visible Light-mediated Nucleophilic Addition of Alkenes to Aldehydes:Efficient Synthesis of Secondary Alcohols
摘要
Abstract
A series of secondary alcohol compounds were prepared by using 2,4,5,6-tetra-(9-carbazolyl)-m-phthalonitrile(4DPAIPN)as photocatalyst,1,8-diazo-diclospirone[5.4.0]undecan-7-ene(DBU)as additive,sodium formate as reducing agent and dimethyl sulfoxide(DMSO)as solvent.The effects of various photocatalysts,additives,reducing agents and solvents on the reaction yield were investigated,and various substituted benzaldehyde and styrene derivatives were expanded.The results showed that the catalytic system has good substrate universality and functional group compatibility,with yields ranging from 50％to 74％.关键词
醇/烯烃/醛/可见光催化/亲核加成Key words
alcohol/olefin/aldehyde/visible light catalysis/nucleophilic addition分类
化学引用本文复制引用
沈佳斌,沈超,盛荟茹,杜芸芸,陈丹丹,顾广苗..可见光介导苯乙烯和苯甲醛亲核加成制备仲醇[J].广州化学,2025,50(2):15-19,5.基金项目
浙江树人学院人才引进项目(KXJ0522111) （KXJ0522111）
