摘要
Abstract
Objective To explore the clinical efficacy of nasal endoscopic surgery in the treatment of nasal and sinonasal in-verted papilloma(NIP).Methods Eighty NIP patients admitted to our hospital from November 2019 to November 2021 were selected and randomly assigned to a control group and an observation group,with 40 cases in each group.The control group underwent traditional surgery,while the observation group received nasal endoscopic surgery.Surgical indicators,in-flammatory response,pain levels,sleep status,ventilation and olfactory functions,recurrence,and complications were compared between the two groups.Results No statistically significant difference was observed in the time of operation be-tween the two groups(P>0.05).The observation group had significantly shorter length of hospital stay and less intraoper-ative blood loss than the control group(P<0.05).Before treatment,there were no significant differences in tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),or interleukin-6(IL-6)levels between the two groups(P>0.05).After treatment,the observation group exhibited lower levels of each indicator than the control group(P<0.05).Visual Analog Scale(VAS)scores at 1 h,8 h,24 h,and 48 h postoperatively were significantly lower in the observation group than in the control group,while postoperative sleep duration on day 1 and day 2 was significantly longer in the observation group(P<0.05).Before treatment,no significant differences were noted in ventilation or olfactory function scores between the two groups(P>0.05).After treatment,both groups showed significant reductions in these scores,with the observation group scoring significantly lower than the control group(P<0.05).The recurrence rate and complication rate in the observation group,stratified by Krouse classification,were 5.00%and 7.50%,respectively,significantly lower than the control group's 20.00%and 25.00%(P<0.05).Conclusion Nasal endoscopic surgery for NIP reduces intraoperative blood loss,short-ens the length of hospital stay,alleviates inflammatory responses,lowers pain levels,prolongs sleep duration,improves ventilation and olfactory functions,reduces recurrence rates,and demonstrates high safety and clinical value.关键词
鼻内镜手术/鼻腔鼻窦内翻性乳头状瘤/传统手术/疼痛水平/炎症反应Key words
Nasal endoscopic surgery/Nasal and sinonasal inverted papilloma/Traditional surgery/Pain level/Inflammatory response分类
医药卫生
