摘要
Abstract
Objective To investigate the impact of central corneal thickness(CCT),anterior chamber depth(AD),lens thickness(LT),axial length(AL),mean corneal radius of curvature(CR),and axial ratio(AL/CR)on the refractive sta-tus of adolescents,and to assess the diagnostic value of AL/CR for myopia.Methods This retrospective study analyzed 4,564 children(9,128 eyes)with suspected refractive errors at our hospital from September 2020 to February 2023.Optical biometry and cycloplegic refraction were recorded to calculate AL/CR and spherical equivalent(SE).Data were analyzed for normality(K-S test),correlation(Pearson),and diagnostic reliability(ROC curve),with SE≤-0.50D as the gold stand-ard of myopia criterion.The reliability of AL/CR as a diagnosis of myopia was analyzed.Results AL,CR,CCT,AD,LT,and AL/CR were correlated with SE(r=-0.754,0.025,-0.024,-0.488,0.408,-0.873;all P<0.05).The ROC AUC values of AL,CR,CCT,AD,LT,and AL/CR were 0.915,0.526,0.523,0.797,0.227,and 0.949,respec-tively.Using AL/CR>3.014 1 as a diagnostic indicator of myopia,its sensitivity,specificity,and accuracy were 0.882,87.75%,and 0.866,respectively,with a Kappa coefficient of 0.714.Conclusion AL/CR is a highly valuable diagnostic in-dicator for myopia in adolescents.关键词
轴率比/近视/ROC曲线/灵敏度/特异度/准确度Key words
Axial ratio/Myopia/ROC curve/Sensitivity/Specificity/Accuracy分类
医药卫生
