摘要
Abstract
Objective To investigate the influencing factors of residual symptoms after canalith repositioning in benign parox-ysmal positional vertigo(BPPV)and to evaluate the intervention effect of betahistine mesylate.Methods A total of 126 BPPV patients admitted to our hospital from June 2019 to January 2022 were selected as the study participants,and all pa-tients underwent canalith repositioning treatment.According to whether residual symptoms were present after treatment,the patients were assigned to the occurrence group(n=61)and the non-occurrence group(n=65).The general information of the two groups was compared,the influencing factors of residual symptoms after canalith repositioning in BPPV patients were analyzed,and the changes in Dizziness Handicap Inventory(DHI)scores as well as the therapeutic efficacy after beta-histine mesylate intervention in patients with residual symptoms were recorded.Results Among the 126 BPPV patients who underwent canalith repositioning treatment,61 patients exhibited residual symptoms,with an incidence rate of 48.41%(61/126).Comparisons between the two groups regarding age,duration of vertigo before repositioning,number of reposi-tioning procedures,combined hypertension,combined diabetes,and vitamin D deficiency all showed statistically significant differences(P<0.05).Advanced age,longer duration of vertigo before repositioning,a higher number of repositioning procedures,concomitant hypertension,concomitant diabetes,and vitamin D deficiency were identified as risk factors for the occurrence of residual symptoms after canalith repositioning in BPPV patients(P<0.05).In patients with residual symp-toms,the post-treatment DHI scores were significantly lower than the pre-treatment scores(P<0.05).The overall re-sponse rate of betahistine mesylate treatment in these patients was 90.16%(55/61).Conclusion BPPV patients may de-velop residual symptoms after canalith repositioning,and their occurrence is associated with multiple factors.Intervention with betahistine mesylate can ameliorate vertigo symptoms,with marked therapeutic efficacy.关键词
良性阵发性位置性眩晕/影响因素/残余症状/耳石复位/甲磺酸倍他司汀Key words
Benign paroxysmal positional vertigo/Influencing factors/Residual symptoms/Canalith repositioning/Betahistine mesylate分类
医药卫生
