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PS-b-PEO本体自组装制备聚合物立方体及生物应用

刘晓 时绪智 吴亭亭 党柯清 苏晓丹

广州化学2025,Vol.50Issue(2):66-70,5.
广州化学2025,Vol.50Issue(2):66-70,5.DOI:10.16560/j.cnki.gzhx.20250209

PS-b-PEO本体自组装制备聚合物立方体及生物应用

Preparation and Biological Application of Polymer Cubes by PS-b-PEO Self-assembly

刘晓 1时绪智 1吴亭亭 1党柯清 2苏晓丹1

作者信息

  • 1. 南京邮电大学材料科学与工程学院,江苏南京 210023
  • 2. 南京邮电大学传媒与艺术学院,江苏 南京 210023
  • 折叠

摘要

Abstract

Using amphiphilic block copolymer PS637-b-PEO161 as a template and combined with microfluidic technology,the continuous preparation of ordered polymer cubes(PCs)was achieved.The results of scanning electron microscopy(SEM)and transmission electron microscopy(TEM)showed an ordered pore structure on the spherical surface of PCs.The sectioning results of focused ion beam scanning electron microscopy(FIB)showed that PCs have rich pore structures.The fluorescence confocal microscopy(LSCM)results showed that PCs had significant adsorption capacity for bovine serum albumin(BSA).Cytotoxicity experiments have shown that the material has good biocompatibility.

关键词

嵌段共聚物/自组装/微流控/聚合物立方体

Key words

block copolymer/self assembly/microfluidics/polymer cubosome

分类

化学化工

引用本文复制引用

刘晓,时绪智,吴亭亭,党柯清,苏晓丹..PS-b-PEO本体自组装制备聚合物立方体及生物应用[J].广州化学,2025,50(2):66-70,5.

基金项目

国家自然科学基金(2227050630) (2227050630)

广州化学

1009-220X

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