河南中医2025，Vol.45Issue(5)：674-681,8.DOI:10.16367/j.issn.1003-5028.2025.05.0110
经典名方桂枝加厚朴杏子汤古今文献考证
Textual Research on Historical and Modern Literature Review of the Classic Famous Formula Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel
摘要
Abstract
Objective:To systematically examine ancient and modern literature on the classic famous formula Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel using bibliometric methods to clarify its historical evolution,identify key informational elements,and analyze its modern clinical applications.Methods:Ancient Literature Analysis:Chinese medical classics published before 1911 were retrieved from databases such as the Airusheng Chinese Medical Classics Database and overseas Chinese medical archives,u-sing keywords including"Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel."A total of 21 valid ancient works were included.Modern Literature:Computerized searches of CNKI,Wanfang Data,and VIP Information databases were conducted with"Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel"and its synonyms as subject terms or keywords,cov-ering records from database inception to July 2024.Results:The study reviewed 63 ancient works,with 21 confirmed as valid.Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel first appeared in Zhang Zhongjing's Treatise on Cold Damage Diseases during the Eastern Han Dynasty.Subsequent medical works largely adhered to the original formula,which is indicated for"pre-existing asthma aggravated by wind-cold invasion presenting with Cinnamon Twig Decoction syndrome"or"mild dyspnea persisting after im-proper use of purgatives for wind-cold exterior syndromes."Its therapeutic mechanism involves releasing muscle tension,dispelling wind,and suppressing qi to relieve wheezing.The formula is composed of seven herbs:Guizhi(Ramulus Cinnamomi),Gancao(Radix Glycyrrhizae),Shengjiang(Rhizoma Zingiveris Recens),Shaoyao(Radix Paeoniae Alba),Houpo(Cortex Magnoliae Officinalis),Xin-gren(Semen Armeniacae Amarum),and Dazao(Fructus Jujubae).However,dosage variations exist across works,with decoction pre-pared via boiling and administered warm.Modern Clinical Applications:The formula is widely used for respiratory diseases(e.g.,bron-chial asthma,chronic bronchitis,chronic obstructive pulmonary disease)and circulatory disorders(e.g.,acute heart failure,chronic pulmonary heart disease),demonstrating significant efficacy.Conclusion:As a classic famous formula,Cinnamon Twig Decoction Plus O-fficinal Magnolia Bark and Apricot Kernel exhibits a well-documented historical evolution,broad clinical utility,and remarkable effica-cy.关键词
桂枝加厚朴杏子汤/经典名方/信息考证/《伤寒论》/张仲景Key words
Cinnamon Twig Decoction Plus Officinal Magnolia Bark and Apricot Kernel/classic famous formula/informational textual re-search/Treatise on Cold Damage Diseases/Zhang Zhongjing分类
医药卫生引用本文复制引用
王永利,李蒙,林俊佐,聂莎,陈两广,王嘉伟,陈嘉祺,汤鹏飞,唐耀平..经典名方桂枝加厚朴杏子汤古今文献考证[J].河南中医,2025,45(5):674-681,8.基金项目
国家自然科学基金项目(82160856) （82160856）
广西壮族自治区自然科学基金重点研发计划项目(桂科AB23026143) （桂科AB23026143）
