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首页|期刊导航|扬州大学学报(农业与生命科学版)|白藜芦醇提高试验小鼠卵子质量及胚胎发育率的促生产效应

白藜芦醇提高试验小鼠卵子质量及胚胎发育率的促生产效应

李秀秀 李晓亚 田镇豪 刘翔宇 杨海明 崔月花

扬州大学学报(农业与生命科学版)2025,Vol.46Issue(2):25-31,7.
扬州大学学报(农业与生命科学版)2025,Vol.46Issue(2):25-31,7.DOI:10.16872/j.cnki.1671-4652.2025.02.004

白藜芦醇提高试验小鼠卵子质量及胚胎发育率的促生产效应

Promoting effect of resveratrol on egg quality and embryo development rate of experimental mice

李秀秀 1李晓亚 2田镇豪 3刘翔宇 4杨海明 5崔月花6

作者信息

  • 1. 扬州大学生物科学与技术学院,江苏扬州 225009||常州卡文斯实验动物有限公司,江苏常州 213100
  • 2. 南开大学分子微生物学与技术教育部重点实验室,天津 300457
  • 3. 西北工业大学生命学院,西安 710129
  • 4. 常州卡文斯实验动物有限公司,江苏常州 213100
  • 5. 扬州大学动物科学与技术学院,江苏扬州 225009
  • 6. 扬州大学生物科学与技术学院,江苏扬州 225009
  • 折叠

摘要

Abstract

To investigate the effects of resveratrol(RSV)on ovulation volume,fertilized egg development,and litter yield of mice,18 aged 3-4 weeks C57BL/6J female mice were intraperitoneally injected with pregnant horse serum hor-mone(PMSG,10 U per mouse)for hyperexcretion as a blank control group,18 mice in the experimental group were sim-ultaneously intraperitoneally injected with RSV and 18 mice in the negative control group were simultaneously injected with dimethyl sulfoxide(the volume fraction was 1% DMSO).The number of ovulated eggs,in vitro fertilization ability of eggs,developmental ability of fertilized eggs in recipient mice,and post transplant litter rate in each group of mice were observed and analyzed.The results showed that the average number of ovulations and cleavage rate in vitro,blastocyst formation rate,implantation rate and litter rate of fertilized eggs in the uterus of recipient mice with ICR(without RSV injection)in the experimental group were(34.02±5.54),(90.37±1.84)%,(93.89±3.47)%,(68.89±4.19)%,and(51.94±3.76)%,respectively,which were significantly higher than those in the blank group and negative control group(P<0.05).To sum up,intraperitoneal injection of RSV can significantly improve the reproduction performance and effi-ciency of experimental mice during superovulation.

关键词

小鼠/白藜芦醇/胚胎发育/产仔率

Key words

mice/resveratrol/embryonic development/litter rate

分类

农业科技

引用本文复制引用

李秀秀,李晓亚,田镇豪,刘翔宇,杨海明,崔月花..白藜芦醇提高试验小鼠卵子质量及胚胎发育率的促生产效应[J].扬州大学学报(农业与生命科学版),2025,46(2):25-31,7.

基金项目

江苏省现代农业产业技术体系建设专项[2023(453)] (453)

扬州大学学报(农业与生命科学版)

OA北大核心

1671-4652

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