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疾病相关的肠道菌群微生态在肺损伤形成的机制研究

朱倩梅 李清扬 车璐 黄宇光

基础医学与临床2025,Vol.45Issue(5):681-685,5.
基础医学与临床2025,Vol.45Issue(5):681-685,5.DOI:10.16352/j.issn.1001-6325.2025.05.0681

疾病相关的肠道菌群微生态在肺损伤形成的机制研究

Disease-associated gut microbiota involvement and its mechanisms in the lung injury

朱倩梅 1李清扬 2车璐 1黄宇光1

作者信息

  • 1. 中国医学科学院北京协和医学院北京协和医院麻醉科,北京 100730
  • 2. 中国医学科学院北京协和医学院,北京 100730
  • 折叠

摘要

Abstract

The gut microbiota is generally thought in regulating the body's metabolism and immune function.The imbalance of gut microbiota is related to the occurrence and development mechanisms of acute and chronic lung dis-eases,resulting from lung injury.The"gut-lung axis"pays a main role in various ways in the occurrence of lung injury,including intestinal barrier dysfunction,reduced diversity of gut microbiota,decreased secretion of beneficial metabolites,translocation of gut microbiota and metabolites to the lungs,immune damage to the body and lungs,increased inflammatory response in the lungs.

关键词

肠道菌群/肺损伤/免疫/围术期

Key words

gut microbiota/lung injury/immunity/perioperative

分类

医药卫生

引用本文复制引用

朱倩梅,李清扬,车璐,黄宇光..疾病相关的肠道菌群微生态在肺损伤形成的机制研究[J].基础医学与临床,2025,45(5):681-685,5.

基金项目

北京协和医院中央高水平医院临床科研专项(022-PUMCH-B-006) (022-PUMCH-B-006)

基础医学与临床

1001-6325

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