军事医学2025，Vol.49Issue(3)：227-232,6.DOI:10.7644/j.issn.1674-9960.2025.03.010
焦虑、恐惧与免疫炎症反应关系的研究进展
Research progress in the relationship between anxiety,fear and immune inflammatory responses
摘要
Abstract
Anxiety and fear,as common symptoms of psychiatric disorders,remain inadequately understood in terms of their pathogenesis.Changes in immune inflammation are considered to play a significant role in both the pathological and physiological processes associated with these mental illnesses.In recent years,it has been demonstrated that stress can regulate immune inflammation through multiple pathways,including the regulation of the autonomic nervous system,the hypothalamic-pituitary-adrenal axis,indoleamine 2,3-dioxygenase and its metabolite kynurenine,and the gut-brain axis.These pathways are implicated in the onset and treatment of anxiety and fear-related mental illnesses.This article focuses on the relationships between anxiety and fear-related mental illnesses and immune inflammatory responses.关键词
焦虑/恐惧/免疫炎症/应激Key words
anxiety/fear/immune inflammation/stress分类
临床医学引用本文复制引用
贺杜鹃,张梅奎,倪寒,段婧瑶,张黎明..焦虑、恐惧与免疫炎症反应关系的研究进展[J].军事医学,2025,49(3):227-232,6.基金项目
科技创新2030(2021ZD0202000) （2021ZD0202000）
西安市第二批陕西西府张氏内科脑病学术流派传承工作室 （）
