昆明医科大学学报2025，Vol.46Issue(4)：157-162,6.DOI:10.12259/j.issn.2095-610X.S20250421
伐尼克兰联合尼古丁贴剂治疗烟草依赖的研究进展
Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence
摘要
Abstract
China has the highest number of smokers in the world with more than 1 million tobacco-related deaths each year.Smoking cessation is a feasible intervention to reduce the prevalence of smoking-related diseases and premature deaths.The smoking cessation therapies approved for use in China are ineffective for some tobacco dependent patients.In order to further improve the rate of smoking cessation,a combination of medications can be chosen,including varenicline combined with nicotine replacement therapy.However,there are conflicting evaluation conclusions on the effectiveness and safety of combination therapy.This article aims to review the mechanism of action,efficacy,and safety of varenicline combined with nicotine replacement therapy in the treatment of tobacco dependence,aiming to provide a basis for this combination therapy.关键词
伐尼克兰/尼古丁贴剂/烟草依赖/联合疗法/疗效Key words
Varenicline/Nicotine patch/Tobacco dependence/Combination therapy/Efficacy分类
医药卫生引用本文复制引用
韦秋琦,赵文倩,刘凌..伐尼克兰联合尼古丁贴剂治疗烟草依赖的研究进展[J].昆明医科大学学报,2025,46(4):157-162,6.基金项目
国家自然科学基金(81960011) （81960011）
