环境与职业医学2025，Vol.42Issue(4)：490-496,7.DOI:10.11836/JEOM24367
微纳米塑料暴露对生殖健康影响的研究进展
Research progress on impact of micro/nanoplastics exposure on reproductive health
摘要
Abstract
Micro/nanoplastics(MNPs),recognized as emerging environmental pollutants,are widely distributed in natural environments.Due to their small particle size and significant migratory ca-pacity,MNPs can infiltrate diverse environmental matrices,then invade and accumulate in the organism via the skin,respiration,and digestion.Recently,concerns have grown over the detri-mental effects and potential toxicity of MNPs on reproductive health.This review summarized published epidemiological and toxicological studies related to MNPs exposure and their effects on reproductive health.Firstly,this review critically examined the current landscape of epidemi-ological evidence and found that MNPs(e.g.,polystyrene,polypropylene,polyvinyl chloride,polyethylene,etc.)are present in various biological specimens from both males and females,and their presence may be associated with an increased risk of reproductive disorders.Secondly,ex-tensive toxicological studies revealed that MNPs exposure induces reproductive health damage through mechanisms such as disrupting the microstructure of reproductive organs and altering molecular-level expressions.Oxidative stress,inflammatory responses,and apoptosis are identi-fied as potential links between MNPs exposure and reproductive damage.Finally,this review ad-dressed the prevalent shortcomings in existing studies and proposed future directions to tackle the challenges posed by MNPs-induced reproductive harm.These insights aim to inform strategies for safeguarding public reproductive health and ecological security,providing a scientific founda-tion for mitigating risks associated with MNPs pollution.关键词
微塑料/纳米塑料/男(雄)性生殖健康/女(雌)性生殖健康/毒性作用Key words
microplastic/nanoplastic/male reproductive health/female reproductive health/toxic effect分类
预防医学引用本文复制引用
黄燕,陈亨贵,黄媛媛,卓彦希,林艺琴,李启鹏,郑小凤,王文祥,李昱辰,邵文亚..微纳米塑料暴露对生殖健康影响的研究进展[J].环境与职业医学,2025,42(4):490-496,7.基金项目
福建医科大学启航基金项目(2023QH1007) （2023QH1007）
