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职业健康风险评估模型中化学物接触参数赋值的思考

丁佳韵 刘美霞 张济明 尹艳 周志俊

环境与职业医学2025,Vol.42Issue(4):497-502,511,7.
环境与职业医学2025,Vol.42Issue(4):497-502,511,7.DOI:10.11836/JEOM24398

职业健康风险评估模型中化学物接触参数赋值的思考

Assignment of chemical exposure parameter in occupational health risk assessment models:Key consideration

丁佳韵 1刘美霞 2张济明 1尹艳 2周志俊1

作者信息

  • 1. 复旦大学公共卫生学院/公共卫生安全教育部重点实验室,上海 200032
  • 2. 上海市疾病预防控制中心健康危险因素监测与控制所,上海 200336
  • 折叠

摘要

Abstract

The core idea of occupational health risk assessment models is to systematically evaluate occupational health risks according to target hazard characteristics and relevant exposure levels of workers.Occupational exposure assessment is based on concentration,frequency,exposure time,and other indicators that indicate actual exposure of workers to occupational hazards,which is a critical component of health risk assessment.However,the accuracy and comparability of assessment results are affected by differences in parameter assignment for exposure assess-ment across different studies,as well as insufficient emphasis on multiple occupational hazard exposure.This review aimed to explore the assignment and standardization of exposure assess-ment parameters for occupational health risk assessment modeling,and systematically sorted out the meaning,assignment methods,and sources of exposure assessment related parameters in commonly used occupational health risk assessment models,with the goal of providing re-searchers with standardized assessment tools to enhance the scientific rigor and practicality of occupational health risk assessments.Considering the individual differences and temporal fluc-tuations in occupational exposure,it is recommended that researchers should adopt appropriate sampling strategies,reasonably select sample subjects and time based on the division of similar exposure group(SEG),and conduct statistical inference on the obtained data to derive represen-tative exposure parameters.For combined exposure to chemicals with similar toxic effects,the health risk assessment methods are relatively mature.However,the assessment of combined exposure to hazards with different properties and health effects still lacks scientific authority and needs further research and discussion.

关键词

职业健康风险评估/相似接触组/接触评估/参数赋值/联合暴露

Key words

occupational health risk assessment/similar exposure group/exposure evaluation/parameter assignment/combined exposure

分类

医药卫生

引用本文复制引用

丁佳韵,刘美霞,张济明,尹艳,周志俊..职业健康风险评估模型中化学物接触参数赋值的思考[J].环境与职业医学,2025,42(4):497-502,511,7.

基金项目

上海市三年行动计划项目(GWVI-11-1-37&41和GWVI-4) (GWVI-11-1-37&41和GWVI-4)

环境与职业医学

OA北大核心

2095-9982

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