扬州大学学报（农业与生命科学版）2025，Vol.46Issue(2)：16-24,9.DOI:10.16872/j.cnki.1671-4652.2025.02.003
福建部分地区犬细小病毒的检测与遗传进化分析
Detection and genetic evolution analysis of canine parvovirus in some areas of Fujian Province
摘要
Abstract
In order to understand the main epidemic trends and molecular evolution characteristics of canine parvovirus in some areas of Fujian province,this study detected canine parvovirus in dog feces collected from 2019 to 2022.The VP2 full-length gene of the positive samples was sequenced,and then the genetic evolution analysis was performed.The re-sults showed that 147 out of 217 samples were positive for canine parvovirus and the infection rate was 67.74％.Thirty-one strains of CPV-2c(75.61％),8 strains of New CPV-2a(19.51％)and 2 strains of New CPV-2b(4.88％)were identified.CPV-2c was the main subtype of canine parvovirus circulating in some areas of Fujian province from 2019 to 2022.Phylogenetic analysis revealed 7 amino acid mutations in the isolated strains.The strains belonged to the same branch with the epidemic strains of subtypes in China from 2008 to 2022,and had a high genetic relationship.The strains were far from the strains isolated in the United States,Japan and Italy,and had obvious regional characteristics.This study enriches the genomic information database of canine parvovirus,and provides a certain reference for monitoring the variation of canine parvovirus,regional epidemic trend and vaccine development.关键词
犬细小病毒/VP2基因/检测/遗传进化Key words
canine parvovirus/VP2 gene/detection/genetic evolution分类
农业科技引用本文复制引用
陆畅,曾显成,陈叶,翟谧,王晓燕,林炫孜,全锦洋,许宇擎,黄俏,肖晓红,陈囿霖,彭栩东..福建部分地区犬细小病毒的检测与遗传进化分析[J].扬州大学学报（农业与生命科学版）,2025,46(2):16-24,9.基金项目
国家重点研发计划项目(SQ2023YFD1800003) （SQ2023YFD1800003）
国家自然科学基金青年基金项目(3230190748) （3230190748）
福建省自然科学基金资助项目(2023J01272) （2023J01272）
福建农林大学科技创新基金项目(KFB23094) （KFB23094）
