临床误诊误治2025，Vol.38Issue(9)：71-76,6.DOI:10.3969/j.issn.1002-3429.2025.09.012
武汉地区老年发热呼吸道症候群流行病学特征及季节性分析
Epidemiological Characteristics and Seasonal Analysis of Elderly Patients with Febrile Respiratory Syndrome in Wuhan Area
摘要
Abstract
Objective To analyze the epidemiological characteristics and seasonal variation of febrile respiratory syn-drome(FRS)in the elderly in Wuhan area.Methods A total of 468 specimens were collected from elderly patients with FRS in the sentinel hospitals in Wuhan from January 2021 to December 2023.The specimens were detected by multiplex real-time PCR,and the positive results were analyzed.Results Of 468 samples from elderly patients with FRS,254 positive specimens were detected,and the total positive rate was54.27%.There was no significant difference in the positive detection rate between male and female samples(P＞0.05).A total of 21 pathogens were detected in468 specimens,and the top 5 pathogens were Streptococcus pneumoniae(n=132,51.97%),Haemophilus influenzae(n=65,25.59%),influenza virus(n=32,12.60%),respiratory syncytial virus(n=29,11.42%)and rhinovirus(n=19,7.48%).There was no signifi-cant difference in the detection rates of the top 5 pathogens among patients with different ages and genders(P＞0.05).There was no significant difference in the detection rate of the top 5 pathogens from 2021 to 2023(P＞0.05).The top five patho-gens showed obvious periodic changes,and the detection rate was the highest in winter(P＜0.05).Among them,Streptococ-cus pneumoniae infection had obvious seasonal characteristics,with a high incidence in winter(P＜0.05).Conclusion Streptococcus pneumoniae,Haemophilus influenzae,influenza virus,respiratory syncytial virus and rhinovirus are the main pathogens in elderly patients with FRS in Wuhan area,and the infection peak season is winter.关键词
发热呼吸道症候群/老年/流行情况/季节性/肺炎链球菌/流感嗜血杆菌/呼吸道合胞病毒Key words
Febrile respiratory syndrome/Elderly/Prevalence of diseases/Seasonality/Streptococcus pneumoniae/Haemophilus influenzae/Respiratory syncytial virus分类
医药卫生引用本文复制引用
李倩,魏婷,柳湘洁,刘晓霞,夏明,魏亮,梁丽媛,张丽萍..武汉地区老年发热呼吸道症候群流行病学特征及季节性分析[J].临床误诊误治,2025,38(9):71-76,6.基金项目
湖北省2023-2024年度中医药科研立项项目(ZY2023M021) （ZY2023M021）
