器官移植2025，Vol.16Issue(3)：359-367,9.DOI:10.12464/j.issn.1674-7445.2025119
2024年肾脏移植研究大盘点:来自中国的声音
Research highlights of kidney transplantation in 2024:voice from China
摘要
Abstract
Kidney transplantation is a crucial treatment modality for patients with end-stage renal disease.However,it still faces numerous challenges,including a severe imbalance between supply and demand,ischemia-reperfusion injury,rejection,infection,and chronic allograft dysfunction.In the past year,with the development of genetic modification technologies,immune regulation strategies,new materials and technologies,in-depth research into pathogenic mechanisms,and breakthroughs in xenotransplantation,significant progress has been made in the field of kidney transplantation.This article reviews the main advances in kidney transplantation research by domestic research teams in 2024,with a focus on the application of new materials and technologies in kidney transplantation research,the mechanisms and treatment strategies for ischemia-reperfusion injury,rejection,infection management,and chronic graft dysfunction,as well as the development of xenotransplantation in China.It also provides a commentary based on the latest research literature,exploring future research directions and clinical application prospects.关键词
肾移植/缺血-再灌注损伤/排斥反应/慢性移植物功能障碍/异种移植/感染/移植物功能延迟恢复/人工智能Key words
Kidney transplantation/Ischemia-reperfusion injury/Rejection/Chronic allograft dysfunction/Xenotransplantation/Infection/Delayed graft function/Artificial intelligence分类
临床医学引用本文复制引用
罗子寰,孙启全..2024年肾脏移植研究大盘点:来自中国的声音[J].器官移植,2025,16(3):359-367,9.基金项目
国家自然科学基金面上项目(82271805、82100797、82270783) （82271805、82100797、82270783）
广州市科技计划项目(2023A04J0498) （2023A04J0498）
广东省人民医院高层次人才引进计划(KY012021457、KY012021200) （KY012021457、KY012021200）
